Grincal D 500 mg+200 IU (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Algae calcium vitamin d3 |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Treatment of osteoporosis, rickets, osteomalacia, tetany and hypoparathyroidism
- In pregnancy and lactation due to increased demand
- In kidney disease and pancreatitis
- During therapy with antiseizure medications
- The prevention and treatment of Calcium and Vitamin D3 deficiency
Composition
- Calcium Carbonate (Algae Source) BP 1250 mg equivalent to elemental Calcium 500 mg
- Vitamin D3 200 IU as Cholecalciferol USP
Pharmacology
Calcium (Algae Source) is an essential element and plays a vital role in the body. It makes body's framework stronger by building bones. Clinical evidence suggests that calcium is useful for prevention and treatment of osteoporosis and associated fractures. Vitamin D3 is also essential for healthy bones as it aids in calcium absorption from the Gl tract. In addition to this, it stimulates bone formation. Controlled clinical studies show that Calcium and Vitamin D3 have synergistic effects on bone growth as well as in osteoporosis and fracture prevention.
Dosage & Administration
Usual adult dose: 1 tablet in the morning and 1 tablet at night. Tablet should be taken orally.
Interaction
- Calcium salts reduce absorption of bisphosphonates, ciprofloxacin, fluorides, iron, levothyroxine, tetracycline and zinc
- Absorption of calcium salts is reduced by corticosteroids
- Increased risk of hypercalcemia when Calcium and Vitamin D3 given with thiazides and related diuretics
- No clinically significant food drug interaction have been reported
Contraindications
- Hypocalcemia and hypercalciuria
- Metastatic calcification
- Hypersensitivity to any of the components of Calcium and Vitamin D3 preparation
Side Effects
- Irregular heartbeat
- Nausea
- Dry mouth
- Weakness
- Headache
- Metallic taste in mouth
- Muscle or bone pain
- Drowsiness
- High amount of Calcium in blood
- Constipation
- Diarrhoea
- Loss of appetite
Pregnancy & Lactation
Calcium and Vitamin D3 should be used considering the risk-benefit ratio
Precautions & Warnings
Caution should be taken in patients with renal impairment, sarcoidosis, hypercalcemia and hypercalciuria
Use in Special Populations
Not recommended for children under 12 years
Overdose Effects
At high doses it may result in nausea, vomiting, dizziness, anorexia, abdominal cramps, headache, constipation. Treatment includes cessation of therapy & adequate rehydration
Therapeutic Class
Specific mineral & vitamin combined preparations
Storage Conditions
Store below 30°C and away from light & moisture. Keep out of the reach of children