Closid 2 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Osl pharma limited |
| Also available as |
Title
Closid 2 mg Tablet
Categories
- Medication
- Benzodiazepine
- Anti-Epileptic
- Anxiolytic
Description
Closid 2 mg Tablet is indicated for the treatment of panic disorder, with or without agoraphobia, and as an adjunct in the treatment of Lennox-Gastaut Syndrome, akinetic and myoclonic seizures. It exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects through enhancement of GABAergic neurotransmission. The dosage for adults with seizure disorders, panic disorder, and pediatric patients is specified. Closid has minimal interaction with certain drugs, contraindications in patients with hypersensitivity to benzodiazepines or significant liver disease, and potential side effects related to CNS depression. It requires caution in use during pregnancy, lactation, and in populations such as pediatric, geriatric, and those with renal or hepatic impairment. Storage conditions and reconstitution guidelines are also provided. It belongs to the therapeutic class of adjunct anti-epileptic drugs and benzodiazepine hypnotics. The chemical structure includes the molecular formula C15H10ClN3O3.
Dimensions
- N/A
Color Options
- N/A
Functions
- Anticonvulsive
- Sedative
- Muscle Relaxing
- Anxiolytic
- Enhancement of GABAergic Neurotransmission
Materials
- N/A
Technical Specifications
- Initial adult dosage not to exceed 1.5 mg/day for seizure disorders
- Maximum daily dose of 20 mg for adults
- Initial adult dose of 0.25 mg for panic disorder
- Dosage adjustment for pediatric patients based on weight
- Slow intravenous injection for administration
Design Elements
- N/A
Usability Features
- Contraindicated in acute narrow angle glaucoma
- Dosage adjustment required in patients with renal impairment
Dosage & Administration
- Initial adult dose for seizure disorders not to exceed 1.5 mg/day divided into three doses
- Initial adult dose for panic disorder is 0.25 mg given in two divided doses
- Pediatric patients' initial dose based on weight
Interaction
- Minimal alteration of the pharmacokinetics of certain drugs
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Hysteria
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential teratogenic effects
- Advised use only if benefits outweigh risks
- Potential adverse effects on newborns
- Recommendation to discontinue breastfeeding
Precautions & Warnings
- Possible increase in generalized tonic-clonic seizures
Use in Special Populations
- Increased secretion in infants and small children
- Greater pharmacologic effects in geriatric patients
- Minimal impact of renal impairment on pharmacokinetics
- Potential reduction in unbound Closid clearance in liver cirrhosis
Overdose Effects
- Drowsiness
- Ataxia
- Dysarthria
- Nystagmus
- Cardiorespiratory depression
- Coma
- Increased frequency of seizures
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Guidelines for slow intravenous injection
- Dilution ratios for intravenous infusion
Storage Conditions
- Dry place away from light and heat
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-284-clonazepam-chemical-structure-S6GmKrvYS03ZYjOTAtig.svg
Commonly Asked Questions
- Is Closid 2 mg Tablet a sleeping pill?: No
- Can Closid 2 mg Tablet be taken for the longer-term?: To be taken as advised by the doctor
- On stopping Closid 2 mg Tablet what kind of withdrawal symptoms occur?: Difficulty in sleeping, changes in mood, increased sweating, muscle pain, headache, shaking (tremor), restlessness, anxiety
- How can I look for early symptoms of suicidal thoughts and actions?: Pay attention to sudden changes in mood, behaviors, thoughts, feelings; Regular consultation with the doctor recommended
- Does Closid 2 mg Tablet cause weight gain?: Yes, in some cases
- Can Closid 2 mg Tablet affect my memory?: No, it does not affect memory
- Can Closid 2 mg Tablet be harmful if more than the recommended doses are used?: Yes, can cause sleepiness, change in speech, confusion, abnormalities in eye movement