Vasofex XR 2.5 mg (Tablet (Extended Release))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Biopharma limited
Also available as
Vasofex xr 5 mg tablet

Indications

  • Treatment of essential hypertension
  • Treatment of secondary hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and disease
  • Treatment of benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of postsynaptic alpha-1-adrenoreceptors
  • Lowering of blood pressure in supine and standing positions
  • Reduction in left ventricular filling pressure
  • Augmentation of cardiac output

Dosage & Administration

  • Initial therapy with a low starting dose
  • Dosage adjustment based on patient's response
  • Recommended starting dose for left ventricular failure
  • Recommended starting dosage for Raynaud's phenomenon and disease
  • Recommended starting dose for benign prostatic hyperplasia

Interaction

  • No adverse drug interaction reported for specific medication interactions

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Weakness
  • Palpitations
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Liver function abnormalities
  • Pancreatitis
  • Edema
  • Orthostatic hypotension
  • Dyspnea
  • Faintness
  • Tachycardia
  • Nervousness
  • Vertigo
  • Hallucinations
  • Depression
  • Rash
  • Pruritus
  • Impotence
  • Incontinence
  • Priapism
  • Blurred vision
  • Epistaxis
  • Tinnitus
  • Dry mouth
  • Nasal congestion
  • Diaphoresis
  • Fever
  • Arthralgia

Pregnancy & Lactation

  • No teratogenic effects seen in animal testing
  • Caution advised during nursing

Precautions & Warnings

  • Possibility of postural hypotension
  • Caution in patients with left ventricular failure
  • Close monitoring for patients with Raynaud's phenomenon and disease

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended in cases of left ventricular failure due to mechanical obstruction

Overdose Effects

  • Profound drowsiness and depressed reflexes observed in accidental ingestion
  • Support of the cardiovascular system and monitoring of renal function advised

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Store below 30°C
  • Keep away from light and moisture
  • Keep away from reach of children

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