Fevnil 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)
Strip Price: ৳ 25.00

Medicine Details

Category Details
Generic Paracetamol caffeine
Company C2c pharma ltd

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Reduce temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Analgesic properties
  • Antipyretic properties
  • Weak anti-inflammatory activity
  • Caffeine as theophylline-like xanthine derivative
  • Increased solubility and transmembrane permeation of Paracetamol by Caffeine
  • Increased pain threshold and tolerance of pain by Caffeine
  • Vessel tone increase in brain by Caffeine

Dosage & Administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Maximum adult dose: 8 tablets daily
  • Not recommended for children below 12 years

Interaction

  • May reduce serum levels with anticonvulsants
  • May enhance the anticoagulant effect of warfarin
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine within 1 hr of admin
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Contraindicated in severe renal function impairment
  • Contraindicated in hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side Effects

  • Mild side effects
  • Haematological reactions including thrombocytopenia and leukopenia
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy & Lactation

  • Consultation required for pregnant mothers
  • Can be taken whilst breastfeeding

Precautions & Warnings

  • Given cautiously in patients with hepatic or renal failure
  • Given cautiously in patients taking other hepatotoxic medication
  • Prolonged use without consulting a physician should be avoided

Overdose Effects

  • Symptoms of Paracetamol overdose in the first 24 hours
  • Liver damage may become apparent 12 to 40 hours after ingestion
  • Abnormalities of glucose metabolism
  • Metabolic acidosis may occur

Therapeutic Class

  • Non opioid analgesics

Storage Conditions

  • Store in a cool and dry place
  • Protect from light and moisture
  • Keep out of the reach of children

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