Nexven 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company C2c pharma ltd

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment for Zollinger-Ellison Syndrome
  • Treatment for Acid related Dyspepsia
  • Treatment for Duodenal & Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Enteric-coated pellet formulation
  • Specific inhibition of the H+/K+-ATPase
  • Metabolized in the liver by cytochrome P450 enzymes
  • Extensively metabolized in the liver
  • Plasma protein binding is constant over a specific concentration range

Dosage

  • 20 mg or 40 mg Once Daily for 4-8 Weeks (Healing of Erosive Esophagitis)
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for Duodenal ulcer
  • 20-40 mg once daily for Gastric ulcer
  • Dosage varies for IV Injection or IV infusion based on age and condition

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken after mixing with water as per instructions
  • IV Injection should be administered as per specific dilution and time guidelines

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Potential interference with absorption of certain drugs
  • No clinically significant interactions with specific drugs
  • Increased plasma levels of certain drugs when co-administered

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • No difference in types of related adverse events seen during maintenance treatment compared to short term treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion of esomeprazole in milk not studied
  • Breast-feeding should be discontinued if essential use of esomeprazole is considered

Precautions & Warnings

  • Symptomatic response to therapy does not exclude the presence of gastric malignancy
  • Specific instructions for administration for patients with difficulty swallowing capsules
  • Potential use of antacids while taking the medication

Use in Special Populations

  • Safety and effectiveness not established in paediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics expected for patients with renal impairment

Overdose Effects

  • No specific antidote known
  • Symptomatic and supportive treatment recommended
  • Possibility of considering multiple drug ingestion in case of overdose

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place with protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Image representation of chemical structure provided

Common Questions about Nexven 20 mg Capsule

  • Description of Nexven 20 mg Capsule as a proton pump inhibitor
  • Multiple uses including treatment for GERD, ulcers, and excessive stomach acid
  • List of common side effects experienced
  • Recommendation to consult a doctor if pregnant or breastfeeding
  • Information on the typical duration for Nexven 20 mg Capsule to take effect
  • Quick tips for usage and precautions

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