Fexonor 120 mg (Tablet)

Title

• Fexonor 120mg Tablet

Categories

• Antihistamine
• Allergy Relief
• Urticaria Treatment
• Non-sedating Antihistamines

Dosage

• Available in tablet form
• Recommended dosage: 60mg twice daily or 120mg once daily
• Dosage for different age groups: children 6-11 years, children 2-11 years
• Dosage adjustment for impaired renal function

Indications

• Relief of symptoms related to allergic rhinitis (seasonal and perennial)
• Treatment for chronic idiopathic urticaria in adults and children 12 years and older
• Improves health-related quality of life and work/activity productivity

Pharmacology

• Fexofenadine is an inverse agonist of the H1 histamine receptor
• Potent and selective affinity for H1 receptors
• No evidence of significant CNS effects
• Does not cross the blood-brain barrier

Interaction

• No hepatic biotransformation
• Increased level in plasma when coadministered with erythromycin or ketoconazole
• No interaction with omeprazole observed
• Reduction in bioavailability when administered with antacids containing aluminium and magnesium hydroxide

Contraindications

• Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

• Common: headache, drowsiness, dizziness, nausea
• Uncommon: fatigue
• Hypersensitivity reactions: angioedema, chest tightness, dyspnea, flushing, systemic anaphylaxis
• Other reported effects: insomnia, nervousness, tachycardia, diarrhea, rash, pruritus

Pregnancy & Lactation

• No adequate data for use in pregnant women
• Not recommended during breastfeeding
• No human data on effect on fertility

Precautions & Warnings

• Limited data in elderly, renally or hepatically impaired patients
• Administer with care in these special groups
• Patients with history of or ongoing cardiovascular disease should be warned
• Unlikely to produce significant effects on ability to drive or use machines

Special Populations

• Altered pharmacokinetics in patients with renal impairment
• Recommended starting dose in patients with decreased renal function
• No substantial effect in moderate to severe hepatic disease
• Similar adverse events in elderly patients compared to those under 65 years

Overdose Effects

• Reported effects: dizziness, drowsiness, fatigue, dry mouth
• No clinically significant adverse reactions at specified doses
• No established maximum tolerated dose

Therapeutic Class

• Non-sedating antihistamines

Storage Conditions

• Keep in a dry place away from light and heat
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C32H39NO4
• Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-468-fexofenadine-hydrochloride-chemical-structure-HrM3XW8ofnGVhLdcBRox.svg

Common Questions

• Description of Fexonor 120mg Tablet
• Uses of Fexonor 120mg Tablet
• Side effects of Fexonor 120mg Tablet
• Storage and disposal instructions for Fexonor 120mg Tablet
• Potential for causing sleepiness
• Rapid onset and effectiveness
• Relief of outdoor and indoor allergy symptoms
• Coping with dizziness caused by Fexonor 120mg Tablet
• Cautions when taking antacids with Fexonor 120mg Tablet
• Proper administration of Fexonor 120mg Tablet
• Foods/drinks to avoid when taking Fexonor 120mg Tablet
• Potential risk of heart problems
• Quick Tips for using Fexonor 120mg Tablet

Related Brands

• Fexonor 180 mg (Tablet) - osl-pharma-limited