Candicon 50 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by Scedosporium apiospermum and Fusarium Species
- For patients intolerant of or refractory to other therapy
Pharmacology
- Triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral and Injection administration
- Different dosages for body weight categories
- Loading dose regimen and maintenance dose
- Instructions for reconstitution of suspension
- Storage conditions for powder for suspension
Interaction
- CYP3A4, CYP2C9 and CYP2C19 inhibitors and inducers
- Co-administration effects on Candicon dosage and other drugs concentrations
- Effects of Phenytoin or Efavirenz co-administration
Contraindications
- Known hypersensitivity to Voriconazole or any other components
- Co-administration with specified drugs due to risk of serious adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Careful assessment of benefit-risk balance for long term exposure
- Reported cases of Squamous cell carcinoma of the skin (SCC) with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No data found about overdose of Candicon
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Shake the bottle well before reconstitution
- Add specified amount of water to loosen the powder
- Shake the closed bottle vigorously until powder is completely mixed with water
- Store reconstituted suspension between specified temperature range
- Discard suspension 14 days after reconstitution
Storage Conditions
- Keep out of reach of children
- Store in a dry place below specified temperature
- Store powder for suspension between specified temperature range