Reef-D Vita 600 mg+400 IU (Tablet)

Indications

• Treatment and prevention of osteoporosis
• Treatment and prevention of osteomalacia
• Treatment and prevention of tetany
• Treatment and prevention of hypoparathyroidism
• Supplement for inadequate intake of Calcium in childhood diet
• Supplement for rickets
• Supplement for pregnancy and lactation
• Supplement for elderly patients
• Pancreatitis
• Phosphate binder in chronic renal failure

Composition

• Tablet contains 1250 mg Calcium Carbonate USP (Coral source)
• Tablet contains 500 mg of elemental Calcium
• Tablet contains 200 IU Vitamin D USP
• DX tablet contains 1500 mg Calcium Carbonate USP (Coral source)
• DX tablet contains 600 mg of elemental Calcium
• DX tablet contains 400 IU Vitamin D USP
• Effervescent tablet contains 1500 mg Calcium Carbonate (Coral source) USP
• Effervescent tablet contains 600 mg of elemental Calcium
• Effervescent tablet contains 400 IU Vitamin D3 as Cholecalciferol USP

Pharmacology

• Adequate Calcium is vital for bodily functions
• Useful for prevention and treatment of Osteoporosis
• Vitamin D essential for healthy bones and Calcium absorption
• Stimulates bone formation
• Synergistic effects on bone growth
• Coral Calcium sourced for better absorption

Dosage & Administration

• One tablet once or twice daily with plenty of water
• Can be taken with or without food
• Dissolve effervescent tablet in a glass of water and drink orally
• Stir the solution with a spoon before drinking

Interaction

• Thiazide diuretics reduce urinary excretion of calcium
• Systemic corticosteroids reduce calcium absorption
• Concomitant use with ion exchange resins or laxatives may reduce Vitamin D absorption
• Interference with the absorption of tetracycline preparations
• Increased toxicity of cardiac glycosides during treatment
• Calcium products should not be taken within two hours of foods high in oxalic acid and phytic acid

Contraindications

• Hypercalcemia and hyperparathyroidism
• Hypercalciuria and nephrolithiasis
• Hypersensitivity to the components
• Severe renal insufficiencies
• Concomitant digoxin therapy

Side Effects

• Irritation of the GI tract
• Constipation
• Rarely produced hypercalcemia
• Allergic reactions
• Irregular heartbeats
• Nausea
• Vomiting
• Decreased appetite
• Dry mouth
• Drowsiness
• Skin rash reported following Vitamin D supplements
• Mental disturbances

Pregnancy & Lactation

• Daily intake should not exceed 1500 mg calcium and 600 IU cholecalciferol
• Avoid overdoses as they may have adverse effects on the developing fetus
• No indications of teratogenicity in humans
• Can be used during pregnancy and breastfeeding with caution

Precautions & Warnings

• Monitoring of serum calcium levels during long-term treatment
• Renal function should be monitored
• Caution in patients with impairment of renal function
• Risk of soft tissue calcification should be taken into account
• Caution with immobilized patients with osteoporosis
• Consideration of vitamin D dose when prescribing other drugs containing vitamin D
• Additional doses should be taken under close medical supervision

Overdose Effects

• Hypervitaminosis D and hypercalcemia
• Symptoms may include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue
• Treatment involves discontinuation of calcium and other relevant medications
• Monitoring of serum electrolytes, renal function, and diuresis

Therapeutic Class

• Specific mineral and vitamin combined preparations

Storage Conditions

• Store at temperature below 30°C
• Protect from light and moisture
• Keep out of reach of children

Common Questions about Reef-D Vita 600 mg Tablet

• Calcium carbonate and vitamin D3 combination for prevention and treatment of deficiency
• Benefits include prevention of osteoporosis, treatment of rickets and osteomalacia, and improvement of bone health in the elderly
• Contradictions include high levels of calcium or vitamin D in the blood, kidney stones, sarcoidosis, and allergic reactions to ingredients
• Common side effects include constipation, nausea, vomiting, diarrhea, headache, drowsiness, and dry mouth
• Recommended dosage is one tablet per day, taken with food
• Precautions include avoidance during pregnancy or breastfeeding, high levels of calcium or vitamin D in the blood, kidney stones, and allergies to ingredients

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