Emetus 8 mg/4 ml (IM/IV Injection)

Indications

• Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
• Prevention and treatment of post-operative nausea and vomiting
• Prevention of radiotherapy-induced nausea and vomiting

Dosage

• Dosage for Chemotherapy-Induced Nausea and Vomiting in Adults and Pediatric patients
• Dosage for Radiotherapy-Induced Nausea and Vomiting in Adults
• Dosage for Postoperative Nausea and Vomiting in Adults
• Dosage for Pediatrics in the prevention of chemotherapy-induced Nausea and Vomiting
• Dosage for Pediatrics in the prevention of radiotherapy-induced Nausea and Vomiting
• Dosage for Pediatrics in the prevention of postoperative Nausea and Vomiting
• Dosage for Total body irradiation
• Dosage for Single high-dose fraction radiotherapy to the abdomen
• Dosage for Daily fractionated radiotherapy to the abdomen
• Dosage for Postoperative Nausea and Vomiting in Adults/Geriatric/Child of 12 years or over
• Dosage for Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy
• Dosage for Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy
• Dosage for Prevention of nausea and vomiting associated with radiotherapy

Administration

• Oral Soluble Film administration steps

Interaction

• Information about drug-metabolizing enzyme system interaction
• Hepatic cytochrome P-450 drug-metabolizing enzymes interaction

Contraindications

• Hypersensitivity to the drug or any of its components
• Concomitant use of apomorphine

Side Effects

• List of frequently reported adverse events
• Mild or moderate nature of adverse events
• Rare cases of serious adverse events

Pregnancy & Lactation

• Carcinogenic effects study results in rats and mice
• Mutagenicity test results
• Oral administration effects on fertility and reproduction performance
• Reproduction studies results in pregnant rats and rabbits
• Excretion in the breast milk of rats
• Caution for nursing women

Precautions & Warnings

• Reported hypersensitivity reactions
• Not a drug that stimulates gastric or intestinal peristalsis
• Caution for use following abdominal surgery or in patients with chemotherapy-induced nausea and vomiting

Use in Special Populations

• Dosage Adjustment for Patients With Impaired Renal Function
• Dosage Adjustment for Patients With Impaired Hepatic Function
• Information about dosage in pediatric patients 4 years of age or younger
• Dosage adjustment for patients over the age of 65

Therapeutic Class

• Anti-emetic drugs

Storage Conditions

• Storage temperature and conditions

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