Uropine 25 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Euro pharma ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of bipolar disorder
- Maintenance treatment of bipolar I disorder
- Prevention of recurrence of manic, depressive or mixed episodes
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at neurotransmitter receptors
- Antagonist at serotonin 5HT1A and 5HT2 receptors
- Antagonist at dopamine D1 and D2 receptors
- Antagonist at histamine H1 receptors
- Antagonist at adrenergic alpha1 and alpha2 receptors
- Mechanism of action is unknown
Dosage & Administration
- Administered twice daily
- Dosing based on specific disorders
- Dose titration for different disorders
- Different dosing for acute and chronic psychoses, manic episodes, depressive episodes, and maintenance treatment
- Usual effective dose range
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration with thioridazine or carbamazepine
- Co-administration with phenytoin
Contraindications
- Contra-indicated in patients hypersensitive to it
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevations in serum triglyceride levels
- Elevations in total cholesterol
- Decreases in HDL cholesterol
- Weight gain
- Decreased haemoglobin
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Use only if benefits justify potential risks
- Excretion into human milk unknown
- Advice to avoid breastfeeding while taking the medication
Precautions & Warnings
- Risk of suicidal thoughts and clinical worsening
- Caution in patients with known cardiovascular disease
- Caution in patients with cerebrovascular disease
- Caution in patients predisposed to hypotension
- Caution in patients with a history of seizures
- Consideration of dose reduction or discontinuation for tardive dyskinesia
- Discontinuation for neuroleptic malignant syndrome
- Caution in patients with cardiovascular disease or family history of QT prolongation
- Reported cases of severe neutropenia
- Observation of increases in blood glucose and hyperglycemia
Use in Special Populations
- Caution in the elderly
- Caution in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Intensive care procedures recommended
- Treatment of refractory hypotension
- Close medical supervision and monitoring
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of sight and reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light
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