Uropine 100 mg (Tablet)

Indications

• Treatment of acute and chronic psychoses
• Treatment of schizophrenia
• Treatment of bipolar disorder
• Maintenance treatment of bipolar I disorder

Pharmacology

• Atypical psychotropic agent
• Antagonist at multiple neurotransmitter receptors
• Belongs to dibenzothiazepine derivatives

Dosage & Administration

• Administered twice daily
• Dosage titration for different indications
• Total daily dose ranges for different conditions

Interaction

• Caution with medicines causing electrolyte imbalance
• Caution with medicines increasing QT interval

Contraindications

• Contra-indicated in patients hypersensitive to Quetiapine

Side Effects

• Common adverse drug reactions
• Somnolence
• Dizziness
• Dry mouth
• Elevations in serum triglyceride levels
• Weight gain

Pregnancy & Lactation

• Safety and efficacy not established during pregnancy
• Advice for breastfeeding women

Precautions & Warnings

• Risk of suicidal thoughts and self-harm
• Caution in patients with cardiovascular disease
• Caution in patients with a history of seizures
• Possibility of tardive dyskinesia and extrapyramidal symptoms
• Caution in patients with a family history of QT prolongation
• Occasional reports of diabetes in clinical trials

Use in Special Populations

• Caution in elderly patients
• Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

• Survival reported in acute overdoses
• No specific antidote
• Intensive care procedures recommended

Therapeutic Class

• Atypical neuroleptic drugs

Storage Conditions

• Keep out of the sight and reach of children
• Do not use after expiry date
• Store in a cool and dry place away from light

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