Onibest 50 mg (Tablet)

Indications

• Reduces muscle spasm of the intestine, biliary system, bladder, and uterus
• Used for pain related to functional disorders of the digestive tract and biliary system
• Indicated for the treatment of spasm and pain in urological and gynaecological diseases

Pharmacology

• Tiemonium Methylsulphate is a competitive antagonist of Acetylcholine and Histamine
• Inhibits intracellular contractile protein of visceral cell which causes inhibition of visceral spasm and pain

Dosage & Administration

• Adult dosage: 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses
• Children dosage: 3 ml/kg or 6 mg/kg body weight daily in divided doses
• Injection dosage: 1 Tiemonium Methylsulphate Injection 3 times daily through Intravenous or Intramuscular route
• Suppository dosage: 20 mg Tiemonium Methylsulphate suppository two or three times daily through rectal route

Interaction

• Should not be used with other drugs without prior consultation with a registered physician to avoid possible drug interaction

Contraindications

• Not to be used in urethroprostatic disorder involving a risk of urine retention
• Contraindicated in patients with a risk of angle closure glaucoma

Side Effects

• Risk of hypotension & tachycardia in certain individuals

Pregnancy & Lactation

• No teratogenic effects reported in animal studies
• Prudence should be exercised for nursing mothers
• No reported problems with normal use

Precautions & Warnings

• Caution needed in patients with disorders of the prostate, chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal & hepatic insufficiency
• Risks of visual disturbances may make it dangerous to drive or use machines

Use in Special Populations

• Paediatric use safety and effectiveness not established
• Efficacy and safety maintained with increasing age

Overdose Effects

• No available data regarding the overdose of Onibest tablet

Therapeutic Class

• Anticholinergics

Storage Conditions

• Keep in a dry place, away from light and heat
• Keep out of the reach of children

Common Questions about Onibest 50 mg Tablet

• Reduces muscles spasm of the intestine, biliary system, bladder, and uterus
• Used for pain in digestive tract and biliary system as well as spasm and pain in urological and gynaecological diseases

Related Brands

• Tiemis 10 mg/5 ml (Syrup) - osl-pharma-limited
• Tiemis 5 mg/2 ml (IM/IV Injection) - osl-pharma-limited
• Tiemis 50 mg (Tablet) - osl-pharma-limited