Newxone 1 gm/vial (IV Injection)
1 gm vial: ৳ 320.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Ad din pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- Stable in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Excreted unchanged in the urine
- Highly protein bound (95%)
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum dose for children: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation for Intramuscular / Intravenous Injections
- Administration over 2-4 minutes
- Tubing infusion over a period of 30 minutes at concentration between 10 mg/mL and 40 mg/mL
- Patient tolerance test recommended before starting treatment
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Not established safety in human pregnancy
- Caution in lactating mothers
Precautions & Warnings
- Possible anaphylactic shock
- Possible gallbladder sludge
- Blood picture should be checked during prolonged treatment
Use in Special Populations
- Not recommended for neonates if premature and newborn up to 28 days of age
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of the reach of children