Unilin CR 300 mg (Tablet (Controlled Release))

Unit Price: ৳ 2.36 (10 x 10: ৳ 236.00)
Strip Price: ৳ 23.60

Medicine Details

Category Details
Generic Theophylline
Company Opsonin pharma ltd
Also available as
Unilin 120 mg syrup Unilin cr 200 mg tablet

Indications

  • Control of acute asthma
  • Management of chronic asthma (Symptomatic and prophylactic treatment)
  • Control of nocturnal asthma and early morning wheezing
  • Management of chronic obstructive lung disease (Chronic bronchitis and emphysema)
  • Control of apnea of pre-maturity

Pharmacology

  • Theophylline as a bronchodilator
  • Structurally classified as a Methylxanthine
  • Smooth muscle relaxation
  • Suppression of airway response to stimuli
  • Increase in diaphragmatic muscle contraction
  • Half-life influenced by variables

Dosage & administration

  • Individualized dose based on peak serum theophylline concentration
  • Sustained release preparation
  • Administered every 12 hours in adults
  • Administration every 8 hours in some children
  • Recommended maintenance dose by age group

Interaction

  • Concurrent use with xanthine derivatives
  • Increased clearance by certain drugs
  • Reduced clearance by certain drugs
  • Potentiation of hypokalemia
  • Monitoring of serum potassium levels

Contraindications

  • Hypersensitivity to Theophylline or any component of the product

Side effects

  • Rare at normal dosage
  • Gastrointestinal discomfort
  • Headache
  • Nausea
  • Insomnia
  • Hypotension
  • CNS stimulation
  • Diuresis

Pregnancy & lactation

  • Unknown effect on fetal harm
  • Use only if clearly needed during pregnancy
  • Excreted into breast milk
  • Potential toxicity in nursing infants

Precautions & warnings

  • Consideration for drug interactions and physiologic conditions
  • Dosage adjustment prior to therapy initiation and increases
  • Low initial dose followed by slow increase

Use in special populations

  • Low clearance in neonates
  • Dosage selection and serum concentration monitoring in pediatric patients

Therapeutic class

  • Bronchodilator
  • Theophylline & related drugs

Storage conditions

  • Keep out of reach of children
  • Store in cool and dry place
  • Protected from light

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