Edron 10 mg (Tablet)

Unit Price: ৳ 15.00 (10's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Montelukast sodium
Company Edruc limited

Title

Edron 10 mg Tablet

Categories

  • Asthma Medication
  • Allergic Rhinitis Medication
  • Leukotriene Receptor Antagonist

Description

Edron 10 mg Tablet is a selective and orally active leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma, acute prevention of Exercise-Induced Bronchoconstriction (EIB), and relief of symptoms of Allergic Rhinitis (AR) including Seasonal & Perennial Allergic Rhinitis.

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Selective and orally active leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process

Dosage and administration

  • Montelukast 10 mg tablet once daily for adults and adolescents 15 years of age and older
  • Montelukast 5 mg tablet once daily for pediatric patients 6 to 14 years of age
  • Montelukast 4 mg tablet once daily for pediatric patients 2 to 5 years of age
  • Montelukast 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
  • No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
  • No dosage adjustment recommended in patients with renal insufficiency
  • Similar pharmacokinetic profile and oral bioavailability in elderly and younger adults

Interaction

  • No apparent increase in adverse reactions when administered with other asthma therapies
  • No clinically important effects on the pharmacokinetics of certain drugs at recommended clinical dose
  • Used concomitantly with commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital, a hepatic enzyme inducer, modestly decreases the AUC of Edron

Contraindications

  • Hypersensitivity to any component of this product

Side effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy and lactation

  • Crosses the placenta following oral dosing in animals
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions and warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for treatment and management of exercise induced bronchospasm
  • Avoid in patients with known aspirin sensitivity
  • Not shown to truncate bronchoconstrictor response to aspirin in aspirin-sensitive asthmatic patients

Overdose effects

  • Adverse experiences consistent with the safety profile of Edron
  • Usual supportive measures recommended in the event of overdose

Therapeutic class

  • Leukotriene receptor antagonists

Storage conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure: Image available

Commonly asked questions

  • Edron 10 mg Tablet is a selective and orally active leukotriene receptor antagonist
  • Commonly used to treat asthma or allergic rhinitis. It helps keep airways open and easy breathing by blocking leukotrienes
  • Effect can be observed after 1-3 hours of administration
  • Effect lasts for an average duration of 24 hours
  • May be taken with or without food as prescribed by your doctor
  • Use should be avoided in pregnant women unless clearly needed

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