Edron 10 mg (Tablet)
Unit Price: ৳ 15.00 (10's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Edruc limited |
Title
Edron 10 mg Tablet
Categories
- Asthma Medication
- Allergic Rhinitis Medication
- Leukotriene Receptor Antagonist
Description
Edron 10 mg Tablet is a selective and orally active leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma, acute prevention of Exercise-Induced Bronchoconstriction (EIB), and relief of symptoms of Allergic Rhinitis (AR) including Seasonal & Perennial Allergic Rhinitis.
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Selective and orally active leukotriene receptor antagonist
- Inhibits the cysteinyl leukotriene receptor (CysLT1)
- Correlated with the pathophysiology of asthma & allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process
Dosage and administration
- Montelukast 10 mg tablet once daily for adults and adolescents 15 years of age and older
- Montelukast 5 mg tablet once daily for pediatric patients 6 to 14 years of age
- Montelukast 4 mg tablet once daily for pediatric patients 2 to 5 years of age
- Montelukast 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
- No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
- No dosage adjustment recommended in patients with renal insufficiency
- Similar pharmacokinetic profile and oral bioavailability in elderly and younger adults
Interaction
- No apparent increase in adverse reactions when administered with other asthma therapies
- No clinically important effects on the pharmacokinetics of certain drugs at recommended clinical dose
- Used concomitantly with commonly prescribed drugs without evidence of clinical adverse interactions
- Phenobarbital, a hepatic enzyme inducer, modestly decreases the AUC of Edron
Contraindications
- Hypersensitivity to any component of this product
Side effects
- Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
- Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy and lactation
- Crosses the placenta following oral dosing in animals
- Use during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Precautions and warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Can be continued during acute exacerbations of asthma
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for treatment and management of exercise induced bronchospasm
- Avoid in patients with known aspirin sensitivity
- Not shown to truncate bronchoconstrictor response to aspirin in aspirin-sensitive asthmatic patients
Overdose effects
- Adverse experiences consistent with the safety profile of Edron
- Usual supportive measures recommended in the event of overdose
Therapeutic class
- Leukotriene receptor antagonists
Storage conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical structure
- Molecular Formula: C35H36ClNO3S
- Chemical Structure: Image available
Commonly asked questions
- Edron 10 mg Tablet is a selective and orally active leukotriene receptor antagonist
- Commonly used to treat asthma or allergic rhinitis. It helps keep airways open and easy breathing by blocking leukotrienes
- Effect can be observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours
- May be taken with or without food as prescribed by your doctor
- Use should be avoided in pregnant women unless clearly needed