Liam 10 mg (Tablet)

Unit Price: ৳ 10.00 (50's pack: ৳ 500.00)

Medicine Details

Category Details
Generic Montelukast sodium
Company Asiatic laboratories ltd
Also available as
Liam 5 mg chewable tablet

Title

  • Liam 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

Liam 10 mg Tablet is a selective and orally active leukotriene receptor antagonist used for the prophylaxis and chronic treatment of asthma, acute prevention of Exercise-Induced Bronchoconstriction (EIB), and relief of symptoms of Allergic Rhinitis (AR). It works by inhibiting the cysteinyl leukotriene receptor (CysLT1), which is associated with the pathophysiology of asthma & allergic rhinitis.

Indication

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are products of arachidonic acid metabolism and are released from various cells, including mast cells and eosinophils.

Dosage and administration

  • Adults and adolescents:
    • 15 years and older: Montelukast 10 mg tablet once daily
  • Pediatric patients:
    • 6 to 14 years: Montelukast 5 mg tablet once daily
    • 2 to 5 years: Montelukast 4 mg tablet once daily
    • 6 months to 5 years: Montelukast 4 mg oral granules once daily
  • Special cases:
    • Hepatic insufficiency: No dosage adjustment is required
    • Renal insufficiency: No dosage adjustment is recommended
    • Elderly use: No dosage adjustment in the elderly is required

Interaction

Liam has been administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma with no apparent increase in adverse reactions. In drug interaction studies, the recommended clinical dose of Liam did not have clinically important effects on the pharmacokinetics of several drugs.

Contraindications

Montelukast is contraindicated in patients who are hypersensitive to any component of this product.

Side effects

  • Common:
    • Diarrhoea
    • Fever
    • Gastrointestinal discomfort
    • Headache
    • Nausea
    • Vomiting
    • Skin reactions
    • Upper respiratory tract infection
  • Uncommon:
    • Akathisia
    • Anxiety
    • Arthralgia
    • Asthenia
    • Abnormal behavior
    • Depression
    • Dizziness
    • Drowsiness
    • Dry mouth
    • Haemorrhage
    • Irritability
    • Malaise
    • Muscle complaints
    • Oedema
    • Seizure
    • Abnormal sensation
    • Sleep disorders
  • Rare:
    • Angioedema
    • Concentration impaired
    • Disorientation
    • Eosinophilic granulomatosis with polyangiitis
    • Erythema nodosum
    • Hallucination
    • Hepatic disorders
    • Memory loss
    • Palpitations
    • Pulmonary eosinophilia
    • Suicidal tendencies
    • Tremor

Pregnancy and lactation

Montelukast crosses the placenta following oral dosing in rats and rabbits. Caution should be exercised when Montelukast is given to a nursing mother.

Precautions and warnings

Liam should not be used in the reversal of bronchospasm in acute asthma attacks. Patients should have appropriate rescue medication available. Therapy with Liam can be continued during acute exacerbations of asthma.

Overdose effects

In the event of overdose, the usual supportive measures should be employed; e.g., remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring, and institute supportive therapy, if required.

Therapeutic class

  • Leukotriene receptor antagonists

Storage conditions

Store in a cool & dry place below 30°C, protect from light & moisture, and keep out of reach of children.

Chemical structure

  • Molecular formula: C35H36ClNO3S
  • Image: https://medex.com.bd/storage/res/g-res-768-montelukast-sodium-chemical-structure-drK1lRHjspWQ7613gJoZ.svg

Common questions

  • What is Liam 10 mg Tablet?: Liam 10 mg Tablet is a selective and orally active leukotriene receptor antagonist.
  • What is Liam 10 mg Tablet used for?: Liam 10 mg Tablet is commonly used to treat asthma or allergic rhinitis. It helps keep airways open and easy breathing by blocking leukotrienes.
  • How soon can the effect of Liam 10 mg Tablet be observed?: The effect of Liam 10 mg Tablet can be observed after 1-3 hours of administration. Liam 10 mg Tablet is not a fast-acting rescue medicine for asthma attacks and needs to be taken daily to work properly.
  • How long does the effect of Liam 10 mg Tablet last?: The effect of Liam 10 mg Tablet lasts for an average duration of 24 hours.
  • Should I use Liam 10 mg Tablet empty stomach?: Liam 10 mg Tablet may be taken with or without food as prescribed by your doctor.
  • What if I miss a dose of Liam 10 mg Tablet?: If you miss a dose, you may take it as soon as possible. But if it is almost time for your next dose, just skip that dose. Do not double up on doses.
  • Are there any pregnancy warnings for Liam 10 mg Tablet?: Use of Liam 10 mg Tablet in pregnant women should be avoided unless clearly needed.
  • General Instructions:
    • Take Liam 10 mg Tablet exactly as prescribed by your doctor.
    • Do not change your Liam 10 mg Tablet dose or stop using asthma medication without your doctor's advice.
    • Liam 10 mg Tablet is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.
    • Avoid situations or activities that may trigger an asthma attack.
    • Talk to your doctor before using Liam 10 mg Tablet if you're pregnant or breastfeeding. They can help you decide if it's the right choice for you.

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