M-lucas 5 mg (Chewable Tablet)
Unit Price: ৳ 8.50 (3 x 10: ৳ 255.00)
Strip Price: ৳ 85.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1)
- Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma & allergic rhinitis
Dosage & Administration
- Adult dosage: Montelukast 10 mg tablet once daily
- Pediatric dosage (6 to 14 years): Montelukast 5 mg tablet once daily
- Pediatric dosage (2 to 5 years): Montelukast 4 mg tablet once daily
- Pediatric dosage (6 months to 5 years): Montelukast 4 mg oral granules once daily
- No dosage adjustment required for mild-to-moderate hepatic insufficiency or renal insufficiency
- Elderly: No dosage adjustment required
Interaction
- No clinically important effects on the pharmacokinetics of theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, and warfarin
- Safety with a wide range of commonly prescribed drugs observed in clinical studies
Contraindications
- Montelukast is contraindicated in patients who are hypersensitive to any component of this product
Side Effects
- Common side effects: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon side effects: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability
- Rare side effects: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders
Pregnancy & Lactation
- Montelukast crosses the placenta in rats and rabbits
- Caution should be exercised when given to nursing mothers
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment of exercise-induced bronchospasm
- Avoidance in patients with known aspirin sensitivity
- Caution in aspirin-sensitive asthmatic patients
Overdose Effects
- No adverse experiences in the majority of overdosage reports
- Usual supportive measures should be employed in the event of overdose
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C35H36ClNO3S
- Chemical Structure image available
Common Questions
- What is M-lucas 5 mg Chew. Tablet?
- Used for treating asthma or allergic rhinitis
- Effect observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours
- Can be taken with or without food
- Pregnancy warnings should be considered
- General instructions provided