Mokast 4 mg (Chewable Tablet)

Unit Price: ৳ 6.02 (3 x 10: ৳ 180.60)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Montelukast sodium
Company Alco pharma ltd
Also available as
Mokast 10 mg tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Selective and orally active leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis
  • Contributes to airway edema, smooth muscle contraction, and altered cellular activity

Dosage & Administration

  • Dosage for adults and adolescents: Montelukast 10 mg tablet once daily
  • Dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
  • Dosage for pediatric patients 2 years to 5 years of age: Montelukast 4 mg tablet once daily
  • Dosage for pediatric patients 6 months to 5 years of age: Montelukast 4 mg oral granules once daily
  • No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
  • No dosage adjustment recommended in patients with renal insufficiency
  • No dosage adjustment in the elderly is required

Interaction

  • Administered with other therapies used in the prophylaxis and chronic treatment of asthma
  • No clinically important effects on the pharmacokinetics of certain drugs

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta following oral dosing in rats and rabbits
  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Therapy with Mokast can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents
  • Effective in improving airway function in asthmatics with documented aspirin sensitivity

Overdose Effects

  • No adverse experiences in the majority of overdosage reports
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Common Questions about Mokast 4 mg Chewable Tablet

  • Treats asthma or allergic rhinitis
  • Blocks leukotrienes to keep airways open and facilitate easy breathing
  • Effect can be observed after 1-3 hours of administration
  • Lasts for an average duration of 24 hours
  • May be taken with or without food as prescribed by a doctor
  • Use in pregnant women should be avoided unless clearly needed
  • General instructions for usage and precautions

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