Monas 10 mg (Tablet)
Unit Price: ৳ 17.50 (2 x 15: ৳ 525.00)
Strip Price: ৳ 262.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Selective and orally active leukotriene receptor antagonist
- Inhibition of the cysteinyl leukotriene receptor (CysLT1)
- Correlation with the pathophysiology of asthma & allergic rhinitis
- Effects on airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process
Dosage & Administration
- Adult dosage: Montelukast 10 mg tablet once daily
- Pediatric dosage: 5 mg for ages 6-14, 4 mg for ages 2-5, 4 mg oral granules for ages 6 months-5 years
- Safety and efficacy established in pediatric patients
- No dosage adjustment in hepatic or renal insufficiency
- Similar pharmacokinetic profile in elderly and younger adults
Interaction
- No clinically important effects on the pharmacokinetics of certain drugs
- Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
- Potential interaction with phenobarbital
- Recommend appropriate clinical monitoring when co-administered with potent cytochrome P450 enzyme inducers
Contraindications
- Hypersensitivity to any component of this product
Side Effects
- Common symptoms: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon symptoms: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
- Rare symptoms: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy & Lactation
- Crosses the placenta following oral dosing in animals
- Caution should be exercised when given to a nursing mother
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Therapy can be continued during acute exacerbations of asthma
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Caution for patients with known aspirin sensitivity
Overdose Effects
- Majority of reports had no adverse experiences
- Adverse experiences consistent with the safety profile of the product
- Usual supportive measures advised in the event of overdose
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular formula: C35H36ClNO3S
Common Questions about Monas 10 mg Tablet
- Definition of Monas 10 mg Tablet
- Common uses for Monas 10 mg Tablet
- Onset of effect of Monas 10 mg Tablet
- Duration of effect of Monas 10 mg Tablet
- Administration with or without food
- Guidelines for missed dose
- Pregnancy warnings
- General instructions
Molecular Formula
- C35H36ClNO3S