Monocast 4 mg/3.5 gm (Oral Granules)

3.5 gm sachet: ৳ 8.00 (30's pack: ৳ 240.00)

Medicine Details

Category	Details
Generic	Montelukast sodium
Company	Beximco pharmaceuticals ltd
Also available as	Monocast 10 mg tablet Monocast 4 mg chewable tablet Monocast 5 mg chewable tablet

Selective and orally active leukotriene receptor antagonist
Indicated for prophylaxis and chronic treatment of asthma
Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Administration dosage for adults and adolescents 15 years of age and older: Montelukast 10 mg tablet once daily
Administration dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
Administration dosage for pediatric patients 2 years to 5 years of age: Montelukast 4 mg tablet once daily
Administration dosage for pediatric patients 6 months to 5 years of age: Montelukast 4 mg oral granules once daily
No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency
No dosage adjustment is recommended in patients with renal insufficiency
Leukotriene receptor antagonists
Storage: Store in cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children.
Molecular Formula: C35H36ClNO3S
Chemical Structure provided
Effect of Monocast 4 mg/3.5 gm Granules can be observed after 1-3 hours of administration
The effect of Monocast 4 mg/3.5 gm Granules lasts for an average duration of 24 hours
May be taken with or without food as prescribed by the doctor

Prophylaxis and chronic treatment of asthma
Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Adults and adolescents dosage: Montelukast 10 mg tablet once daily
Pediatric patients dosage (6 to 14 years of age): Montelukast 5 mg tablet once daily
Pediatric patients dosage (2 years to 5 years of age): Montelukast 4 mg tablet once daily
Pediatric patients dosage (6 months to 5 years of age): Montelukast 4 mg oral granules once daily
No hepatic or renal insufficiency dosage adjustment
Similar pharmacokinetic profile and bioavailability in elderly and younger adults

No apparent increase in adverse reactions when administered with other therapies
No clinically important effects on the pharmacokinetics of specific drugs
Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
Potent cytochrome P450 enzyme inducers may require appropriate clinical monitoring

Common: Diarrhea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
Uncommon: Dizziness, drowsiness, dry mouth, muscle complaints, sleep disorders
Rare: Angioedema, hallucination, memory loss, palpitations, suicidal tendencies, tremor

Not indicated for use in the reversal of bronchospasm in acute asthma attacks
Appropriate rescue medication should be available
Continued therapy during acute exacerbations of asthma
Should not be abruptly substituted for inhaled or oral corticosteroids
Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
Avoidance of aspirin or non-steroidal anti-inflammatory agents in patients with known aspirin sensitivity
Not shown to truncate bronchoconstrictor response to aspirin in aspirin-sensitive asthmatic patients

Most frequently occurring adverse experiences consistent with the safety profile of the product
Usual supportive measures recommended in case of overdose