Monovas 10 mg (Tablet)
Unit Price: ৳ 15.00 (30's pack: ৳ 450.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | The white horse pharmaceuticals ltd |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Selective and orally active leukotriene receptor antagonist
- Inhibits the cysteinyl leukotriene receptor (CysLT1)
- Correlated with the pathophysiology of asthma & allergic rhinitis
Dosage & Administration
- Dosage for adults and adolescents 15 years of age and older: 10 mg tablet once daily
- Dosage for pediatric patients 6 to 14 years of age: 5 mg tablet once daily
- Dosage for pediatric patients 2 to 5 years of age: 4 mg tablet once daily
- Dosage for pediatric patients 6 months to 5 years of age: 4 mg oral granules once daily
- Efficacy in pediatric patients similar to adults
- No dosage adjustment in hepatic or renal insufficiency
- Similar pharmacokinetic profile in elderly and younger adults
Interaction
- No apparent increase in adverse reactions when administered with other therapies for asthma
- No clinically important effects on the pharmacokinetics of specified drugs
- Used concomitantly with a range of commonly prescribed drugs without clinical adverse interactions
- Phenobarbital decreased the AUC approximately 40%
- Appropriate clinical monitoring when co-administered with potent cytochrome P450 enzyme inducers
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Common: Diarrhea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, hemorrhage, irritability, malaise, muscle complaints, edema, seizure, abnormal sensation, sleep disorders
- Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy & Lactation
- Crosses the placenta in rats and rabbits
- Use during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Appropriate rescue medication should be available
- Can be continued during acute exacerbations of asthma
- Should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment of exercise induced bronchospasm
- Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents
Overdose Effects
- No adverse experiences in majority of reports
- Adverse experiences consistent with safety profile of the product
- Usual supportive measures recommended in the event of overdose
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C35H36ClNO3S
Common Questions about Monovas 10 mg Tablet
- Selective and orally active leukotriene receptor antagonist
- Used to treat asthma or allergic rhinitis
- Effect can be observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours
- May be taken with or without food as prescribed by doctor
- Pregnancy use should be avoided unless clearly needed
- General instructions for usage