Montex 5 mg (Chewable Tablet)

Unit Price: ৳ 8.00 (2 x 10: ৳ 160.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Ibn sina pharmaceuticals ltd
Also available as
Montex 10 mg tablet Montex 4 mg chewable tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Leukotriene receptor antagonist
  • Orally active
  • Inhibits cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis
  • Contributes to airway edema, smooth muscle contraction, and altered cellular activity

Dosage & Administration

  • Adult dosage: 10 mg tablet once daily
  • Pediatric dosage: 5 mg tablet once daily (6-14 years), 4 mg tablet once daily (2-5 years), 4 mg oral granules once daily (6 months - 5 years)
  • No dosage adjustment in mild-to-moderate hepatic insufficiency
  • No dosage adjustment in renal insufficiency
  • Similar pharmacokinetic profile in elderly and younger adults

Interaction

  • No clinically important effects on the pharmacokinetics of certain drugs
  • Concomitant use with a wide range of commonly prescribed drugs
  • Phenobarbital decreased the AUC of Montex approximately 40%

Contraindications

  • Hypersensitivity to any component of the product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta following oral dosing in rats and rabbits
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not for monotherapy for the treatment of exercise induced bronchospasm

Overdose Effects

  • No adverse experiences in the majority of overdosage reports
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

Leukotriene receptor antagonists

Storage Conditions

Store in cool & dry place below 30°C, protect from light & moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Common Questions

  • Used for asthma or allergic rhinitis
  • Effect can be observed after 1-3 hours of administration
  • Effect lasts for an average duration of 24 hours
  • Can be taken with or without food
  • Advice for missed dose and pregnancy warnings

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