Montril 4 mg (Flash Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)

Strip Price: ৳ 70.00

Medicine Details

Category	Details
Generic	Montelukast sodium
Company	Aristopharma ltd
Also available as	Montril 5 mg chewable tablet Montril 10 mg tablet

Prophylaxis and chronic treatment of asthma
Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Selective and orally active leukotriene receptor antagonist
Inhibits the cysteinyl leukotriene receptor (CysLT1)
Correlated with the pathophysiology of asthma & allergic rhinitis
Correlates to airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process

10 mg tablet once daily for adults and adolescents 15 years of age and older
5 mg tablet once daily for pediatric patients 6 to 14 years of age
4 mg tablet once daily for pediatric patients 2 years to 5 years of age
4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
No dosage adjustment recommended in patients with renal insufficiency
Similar pharmacokinetic profile and oral bioavailability in elderly and younger adults

No apparent increase in adverse reactions when administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma
No clinically important effects on the pharmacokinetics of specific drugs at recommended clinical doses
Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
Phenobarbital decreased the AUC of Montril approximately 40% following a single 10mg dose

Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Not indicated for use in the reversal of bronchospasm in acute asthma attacks, including status asthmaticus
Appropriate rescue medication should be available
Therapy can be continued during acute exacerbations of asthma
Should not be abruptly substituted for inhaled or oral corticosteroids
Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
Caution for patients with known aspirin sensitivity
Effective in improving airway function in asthmatics with documented aspirin sensitivity but has not been shown to truncate bronchoconstrictor response to aspirin and other non-steroidal anti-inflammatory drugs in aspirin-sensitive asthmatic patients

Mostly consistent with the safety profile of Montril including abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity
Reasonable to employ the usual supportive measures in the event of overdose