Montril 5 mg (Chewable Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Aristopharma ltd
Also available as
Montril 4 mg flash tablet Montril 10 mg tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Leukotriene receptor antagonist
  • Inhibition of cysteinyl leukotriene receptor (CysLT1)
  • Correlation with asthma & allergic rhinitis pathophysiology
  • Inhibition of airway edema, smooth muscle contraction, and inflammatory cellular activity

Dosage & Administration

  • Dosage for adults (10 mg tablet)
  • Dosage for adolescents (15 years and older)
  • Dosage for pediatric patients (6 to 14 years - 5 mg tablet)
  • Dosage for pediatric patients (2 to 5 years - 4 mg tablet)
  • Dosage for pediatric patients (6 months to 5 years - 4 mg oral granules)
  • Safety and efficacy in pediatric patients
  • No dosage adjustment for hepatic insufficiency
  • No dosage adjustment for renal insufficiency
  • Similar pharmacokinetics in elderly adults

Interaction

  • No significant effects on theophylline pharmacokinetics
  • No effects on prednisone and prednisolone pharmacokinetics
  • No clinically adverse interactions with commonly prescribed drugs
  • Decreased AUC with phenobarbital co-administration
  • Monitoring with potent cytochrome P450 enzyme inducers co-administration

Contraindications

  • Hypersensitivity to any component of the product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses placenta in rats and rabbits
  • Caution during pregnancy and nursing

Precautions & Warnings

  • Not for use in acute asthma attacks
  • Appropriate rescue medication should be available
  • Continuation during acute exacerbations of asthma
  • No abrupt substitution for corticosteroids
  • Not for monotherapy in exercise induced bronchospasm
  • Caution for aspirin-sensitive patients

Overdose Effects

  • Consistent with safety profile of the product
  • Usual supportive measures recommended

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Common Questions about Montril 5 mg Chewable Tablet

  • Purpose and usage
  • Onset and duration of effect
  • Administration with or without food
  • Missed dose instructions
  • Pregnancy warnings
  • General usage instructions

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