Trilock 5 mg (Tablet)

Unit Price: ৳ 8.06 (3 x 14: ৳ 338.52)
Strip Price: ৳ 112.84

Medicine Details

Category Details
Generic Montelukast sodium
Company Opsonin pharma ltd
Also available as
Trilock 4 mg tablet Trilock 10 mg tablet Trilock 4 mg oral granules Trilock oft 4 mg flash tablet Trilock oft 5 mg flash tablet Trilock 10 mg chewable tablet

Title and Category

  • Trilock 5 mg Tablet
  • Medicine
  • Healthcare
  • Pharmaceutical

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Leukotriene receptor antagonist
  • Inhibits cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Adult dosage: Montelukast 10 mg tablet once daily
  • Pediatric dosage: 5 mg for 6-14 years, 4 mg for 2-5 years, 4 mg oral granules for 6 months to 5 years
  • No dosage adjustment for hepatic or renal insufficiency
  • Similar pharmacokinetic profile in elderly

Interaction

  • No apparent increase in adverse reactions with other asthma therapies
  • No clinically important effects on the pharmacokinetics of certain drugs
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of adverse interactions
  • May require clinical monitoring when co-administered with potent cytochrome P450 enzyme inducers

Contraindications

  • Hypersensitivity to any component

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta in animals
  • Use during pregnancy only if clearly needed
  • Caution with nursing mothers due to potential excretion in human milk

Precautions & Warnings

  • Not indicated for use in reversing bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for exercise induced bronchospasm
  • Caution with aspirin-sensitive patients
  • Effective in improving airway function in asthmatics with aspirin sensitivity but does not truncate bronchoconstrictor response to aspirin

Overdose Effects

  • No adverse experiences in majority of reports
  • Usual supportive measures recommended in case of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Commonly Asked Questions

  • Trilock 5 mg Tablet is a selective and orally active leukotriene receptor antagonist
  • Used to treat asthma or allergic rhinitis
  • Effect can be observed after 1-3 hours and lasts for an average duration of 24 hours
  • May be taken with or without food
  • Caution with use in pregnant women
  • General instructions for usage and precautions

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