Trilock 10 mg (Tablet)

Unit Price: ৳ 17.00 (3 x 14: ৳ 714.00)
Strip Price: ৳ 238.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Opsonin pharma ltd
Also available as
Trilock 4 mg tablet Trilock 5 mg tablet Trilock 4 mg oral granules Trilock oft 4 mg flash tablet Trilock oft 5 mg flash tablet Trilock 10 mg chewable tablet

Title

  • Trilock 10 mg Tablet

Categories

  • Medicine
  • Healthcare
  • Pharmacology

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Selective and orally active leukotriene receptor antagonist
  • Inhibitor of the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Adults and adolescents dosage: Montelukast 10 mg tablet once daily
  • Pediatric patients dosage: Montelukast 5 mg, 4 mg tablet, or 4 mg oral granules once daily based on age
  • Safety and efficacy established in pediatric patients with asthma 6 months to 14 years of age
  • No dosage adjustment required in mild-to-moderate hepatic insufficiency or renal insufficiency
  • Elderly use: similar pharmacokinetic profile and oral bioavailability with slightly longer plasma half-life

Interaction

  • No apparent increase in adverse reactions when administered with other asthma therapies
  • Clinical dose did not have clinically important effects on the pharmacokinetics of certain drugs
  • Used concomitantly with a wide range of commonly prescribed drugs without evidence of clinical adverse interactions
  • Phenobarbital decreased the AUC of Trilock by approximately 40% following a single 10mg dose
  • Appropriate clinical monitoring recommended when potent cytochrome P450 enzyme inducers are co-administered

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, etc.

Pregnancy & Lactation

  • Crosses the placenta following oral dosing in rats and rabbits
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Trilock

Overdose Effects

  • Adverse experiences include abdominal pain, somnolence, thirst, headache, vomiting, psychomotor hyperactivity
  • Usual supportive measures recommended in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure: Image available

Common Questions

  • What is Trilock 10 mg Tablet?
  • What is Trilock 10 mg Tablet used for?
  • How soon can the effect be observed?
  • How long does the effect last?
  • Should it be taken empty stomach?
  • What if a dose is missed?
  • Are there any pregnancy warnings?
  • General Instructions for usage

Additional Information

  • Caution in patients with hepatic insufficiency or renal insufficiency
  • No clinically important effects observed in drug interaction studies
  • No clinical adverse interactions reported with commonly prescribed drugs
  • Advice to have appropriate rescue medication available
  • Avoid abrupt substitution for inhaled or oral corticosteroids
  • Avoid aspirin or non-steroidal anti-inflammatory agents in patients with known aspirin sensitivity
  • Supportive measures recommended in case of overdose
  • Store below 30°C and protect from light & moisture

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