Beclomin 100 mcg/puff (Inhaler)

Indications

• Prophylactic management of mild, moderate, or severe asthma in adults and children
• Offers preventative treatment for asthma
• Provides effective anti-inflammatory action in the lungs
• Lower incidence and severity of adverse effects compared to systemic corticosteroids
• Suitable for patients requiring symptomatic bronchodilator asthma medication
• For unstable or worsening asthma despite prophylactic therapy or bronchodilator alone
• For severe chronic asthma and those dependent on systemic corticosteroids
• Potential to reduce or eliminate oral corticosteroid requirement
• Mild, Moderate, and Severe asthma categories described
• Treatment for patients with hepatic or renal impairment

Pharmacology

• Produces anti-inflammatory and vasoconstrictor effects
• Mechanisms responsible for anti-inflammatory action are unknown
• Wide range of effects on multiple cell types and mediators involved in inflammation
• Pro-drug with weak glucocorticoid receptor binding affinity
• Hydrolyzed to active metabolite with high topical anti-inflammatory activity
• No histopathologic changes in nasal mucosa observed during clinical studies

Dosage

• For oral inhalation use only
• Starting dose appropriate to the severity of disease
• Adjustable dose until control is achieved
• Usual starting dose and dosage adjustments for adults and children
• Total daily dose may be administered as two, three, or four divided doses

Administration

• Instructions for correct and regular use of the inhaler
• Steps to use the inhaler effectively
• Guidelines for using the inhaler according to National Asthma Guidelines
• Instructions for cleaning the inhaler
• Importance of checking the technique for inhaler usage

Contraindications

• Hypersensitivity to any of the components
• Special care necessary in patients with active or quiescent pulmonary tuberculosis

Side Effects

• Potential systemic effects at high doses prescribed for prolonged periods
• Possible systemic effects include Cushing's syndrome, Cushingoid features, and adrenal suppression
• Growth retardation in children and adolescents
• Decrease in bone mineral density, cataract, and glaucoma

Pregnancy & Lactation

• Inadequate evidence of safety in human pregnancy
• Potential hazards to the mother and baby during breastfeeding

Precautions & Warnings

• Instruction for proper use of the inhaler and technique check
• Need for regular, daily use even when asymptomatic

Therapeutic Class

• Respiratory corticosteroids

Storage Conditions

• Storage below 30°C, protected from direct sunlight and heat
• Canister should not be broken, punctured or burnt
• Keep away from eyes and out of reach of children

Related Brands

• Beclocort (HFA) 100 mcg/puff (Inhaler) - aristopharma-ltd