Alfacort 40 mg/ml (IM/IA Injection)

1 ml vial: ৳ 60.18 (4's pack: ৳ 240.72)

Medicine Details

Category Details
Generic Triamcinolone acetonide injection
Company Ziska pharmaceuticals ltd

Indications

  • Rheumatic disorders
  • Allergic states
  • Dermatologic diseases
  • Endocrine disorders
  • Gastrointestinal diseases
  • Hematologic disorders
  • Neoplastic diseases
  • Nervous system disorders
  • Ophthalmic diseases
  • Renal diseases
  • Respiratory diseases
  • Trichinosis
  • Bone and joint diseases

Pharmacology

  • Chemical composition: Triamcinolone Acetonide
  • Physical properties: White to cream-colored, crystalline powder
  • Solubility: Insoluble in water, soluble in alcohol
  • Mechanism of action: Synthetic glucocorticoid corticosteroid with anti-inflammatory action
  • Suitable for: Intramuscular and intra-articular use only

Dosage & Administration

  • Initial dosage range: 2.5 mg to 100 mg per day
  • Recommended administration: Deep intramuscular injection
  • Atrophy risk: Atrophy of subcutaneous fat with improper administration
  • Local administration: Intra-articular injection for joint disorders

Interaction

  • Aminoglutethimide interaction
  • Amphotericin B and potassium-depleting agents interaction
  • Antibiotics and corticosteroid clearance
  • Anticholinesterases and severe weakness in myasthenia gravis
  • Anticoagulants, oral, and corticosteroid coadministration
  • Antidiabetics dosage adjustments
  • Drug interactions with cholestyramine, cyclosporine, and ketoconazole
  • Concomitant use with NSAIDs, skin tests, and vaccines

Contraindications

  • Hypersensitivity to any components
  • Idiopathic thrombocytopenic purpura

Side Effects

  • Allergic reactions
  • Cardiovascular effects
  • Dermatologic adverse reactions
  • Endocrine system manifestations
  • Fluid and electrolyte disturbances
  • Gastrointestinal complications
  • Metabolic changes
  • Musculoskeletal effects
  • Neurologic and psychiatric reactions
  • Ophthalmic adverse events

Pregnancy & Lactation

  • Pregnancy Category C
  • Potential teratogenic effects
  • Corticosteroid presence in human milk

Precautions & Warnings

  • Heat sensitivity
  • Risk/benefit decision for dose and duration of treatment
  • Caution in congestive heart failure, hypertension or renal insufficiency
  • Risk of perforation in certain gastrointestinal conditions
  • Systemic absorption of intra-articularly injected corticosteroids

Use in Special Populations

  • Pediatric use caution
  • Greater sensitivity in premature and low-birth-weight infants
  • Geriatric use similarities and potential sensitivity

Overdose Effects

  • Supportive and symptomatic therapy
  • Temporary dosage reduction for chronic overdosage

Therapeutic Class

  • Corticosteroid
  • Glucocorticoids
  • Triamcinolone
  • Combined preparations

Storage Conditions

  • Controlled room temperature storage
  • Avoid freezing and protect from light

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