Bexitrol F 50 mcg+500 mcg (Inhalation Capsule)

Title

• Bexitrol F Inhaler

Categories

• Asthma and COPD Management

Description

• Bexitrol F Inhaler is a combination product indicated in the regular treatment of asthma where the use of a combination product (long-acting beta-2-agonist and inhaled corticosteroid) is appropriate.

Indications

• Regular treatment of asthma
• Combination product for asthma management
• Use for patients inadequately controlled with inhaled corticosteroids
• Use in patients already adequately controlled on inhaled corticosteroid and long-acting beta-2-agonist

Pharmacology

• Selective long-acting beta-2 agonist for asthma treatment
• Corticosteroid with mainly glucocorticoid activity for improved lung function

Dosage

• Variety of inhaler and capsule dosages for different age groups
• Use dosage based on asthma severity
• Molded plastic Maxhaler device with different dosage strengths

Administration

• Proper inhaler use instructions
• Steps for effective inhaler usage
• Instructions for cleaning inhaler

Interaction

• Avoid non-selective and selective beta-blockers in patients with asthma
• Be cautious with known strong CYP3A4 inhibitors

Contraindications

• Hypersensitivity to salmeterol xinafoate or fluticasone propionate

Side Effects

• Adverse effects associated with Salmeterol (e.g., tremor, palpitations, headache)
• Adverse effects associated with Fluticasone Propionate (e.g., hoarseness, candidiasis)

Pregnancy & Lactation

• Consideration for use during pregnancy and lactation
• Insufficient experience in human pregnancy for risk assessment

Precautions & Warnings

• Avoid initiation during asthma exacerbation or unstable asthma
• Be vigilant for serious asthma-related adverse events
• Potential for paradoxical bronchospasm
• Increased reporting of pneumonia in COPD patients
• Possible systemic effects with inhaled corticosteroid at high doses

Use in Special Populations

• Potential impact on growth in paediatric patients

Overdose Effects

• Signs and symptoms of Salmeterol overdose
• Temporary suppression of adrenal function with Fluticasone Propionate overdose

Therapeutic Class

• Long-acting selective β-adrenoceptor stimulants
• Respiratory corticosteroids

Storage Conditions

• Pressurised canister storage precautions
• Avoid direct sunlight or heat
• Store below 30°C

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