Salflu 50 mcg+500 mcg (Inhalation Capsule)

Unit Price: ৳ 17.00 (3 x 10: ৳ 510.00)
Strip Price: ৳ 170.00

Medicine Details

Category Details
Generic Salmeterol fluticasone propionate
Company Acme laboratories ltd
Also available as
Salflu 50 mcg inhalation capsule Salflu 50 mcg inhalation capsule Salflu 25 mcg inhaler Salflu 25 mcg inhaler Axinat f 25 mcg inhaler Axinat f 25 mcg inhaler

Indications

  • Regular treatment of asthma
  • Combination product for inadequately controlled asthma
  • Suitable for patients controlled on both inhaled corticosteroid and long-acting β2-agonist

Pharmacology

  • Selective, long-acting beta-2 agonist
  • Corticosteroid with mainly glucocorticoid activity
  • Selective long-acting (12-hour) beta-2-adrenoceptor agonist
  • Topical effect on the lungs without systemic effects at usual dose

Dosage

  • Multiple strengths for adults and adolescents
  • Different dosages for children (4-12 years)
  • Starting dosages based on asthma severity
  • Maximum recommended dosage
  • Specific dosages for COPD
  • Instructions for using Maxhaler
  • Instructions for special patient groups
  • Rinsing the mouth after each inhalation advised

Administration

  • Importance of correct usage for effectiveness
  • Simple steps to use Inhaler effectively
  • Instructions for cleaning Inhaler

Interaction

  • Avoidance of non-selective and selective β-blockers in asthma patients
  • Unlikelihood of clinically significant drug interactions due to low plasma concentrations
  • Caution with known strong CYP3A4 inhibitors

Contraindications

  • Hypersensitivity to salmeterol xinafoate, fluticasone propionate, or excipients
  • Primary treatment of status asthmaticus or other acute episodes of asthma

Side Effects

  • Potential adverse reactions associated with Salmeterol and Fluticasone Propionate
  • Transient pharmacological side effects of beta-2-agonist treatment
  • Adverse events associated with Fluticasone Propionate
  • Relief measures for candidiasis (thrush) and hoarseness

Pregnancy & Lactation

  • Consideration of expected benefit to mother versus possible risk to fetus or child
  • Insufficient human experience of use during pregnancy and lactation
  • Fetal effects observed in animals at excessive systemic exposure levels

Precautions & Warnings

  • Non-initiation during exacerbation or unstable asthma
  • Not for relief of acute symptoms requiring fast-acting bronchodilator
  • Warning of serious asthma-related adverse events
  • Immediate relief measures for paradoxical bronchospasm
  • Increased reporting of pneumonia in COPD patients
  • Possibility of systemic effects with high doses of inhaled corticosteroids

Use in Special Populations

  • Potential reduction in growth velocity when administered to pediatric patients
  • Unknown long-term effects, including impact on final adult height

Overdose Effects

  • Signs and symptoms of potential overdosage for Salmeterol
  • Potential adrenal suppression due to chronic overdose of Fluticasone Propionate

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants
  • Respiratory corticosteroids

Storage Conditions

  • Importance of not puncturing, breaking, or incinerating the pressurised canister
  • Avoidance of storage in direct sunlight or heat
  • Storage below 30°C
  • Keep away from eyes and children

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