Brofex 10 mg/5 ml (Syrup)

Indications

• Chronic dry cough
• Unproductive cough
• Acute dry cough interfering with normal function or sleep

Composition

• Each 5 ml sugar-free syrup contains Dextromethorphan Hydrobromide BP 10 mg

Pharmacology

• Central action on the cough center in the medulla
• Rapid absorption from GI tract
• Duration of action approximately 3-6 hours
• Extensively metabolized in the liver

Dosage & Administration

• Adults and Children over 12 years: 15 to 30 mg three to four times per day
• Children between 6 and 12 years: 5-15 mg up to four times per day
• Children between 2 and 6 years: 2.5-5 mg up to four times per day

Interaction

• Two fatal interactions reported in patients taking phenelzine and dextromethorphan

Contraindications

• Concomitant use of monoamine oxidase inhibitors
• Prescribed with caution to patients with liver disease

Side Effects

• Rare adverse effects include nausea and dizziness
• No analgesia or addiction
• Excitation, confusion, and respiratory depression may occur after overdosage

Pregnancy & Lactation

• Avoid in the first three months of pregnancy
• Nursing mothers should be advised not to take the drug

Precautions & Warnings

• Do not use to control a cough associated with smoking, asthma, or emphysema
• Do not use for a productive cough

Therapeutic Class

• Cough suppressant

Storage Conditions

• Keep below 30°C
• Away from light & moisture
• Keep out of the reach of children

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