Boxol 6 mg/ml (Pediatric Drops)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ambroxol hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Productive cough
- Acute and chronic inflammatory disorders of upper and lower respiratory tracts
- Inflammatory disease of rhinopharyngeal tract
- Asthmatic bronchitis bronchial asthma
- Bronchiectasis
- Chronic pneumonia
Pharmacology
Ambroxol is the active metabolite of bromhexine and it has a greater bronchosecretolytic effect than bromhexine. It improves sputum rheology, hydrates mechanism leading to liquefaction of mucus, stimulates production of phospholipids of surfactant by alveolar cells, reduces bronchial hyperactivity, and has anti-inflammatory properties.
Dosage & Administration
- Pediatric Drops:
- 0-6 months: 0.5 ml 2 times a day
- 6-12 months: 1 ml 2 times a day
- 1-2 years: 1.25 ml 2 times a day
- Syrup:
- 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
- 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
- 10 years and adults: 10 ml (2 teaspoonful) 3 times a day
- Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily
Interaction
Boxol should not be taken simultaneously with antitussives (e.g. Codeine) because phlegm might not be expectorated.
Contraindications
Known hypersensitivity to Ambroxol or Bromhexine
Side Effects
- Gastrointestinal side effects like epigastric pain, stomach overfill feeling
- Rarely allergic responses such as eruption, urticaria or angioneurotic edema
Pregnancy & Lactation
Teratogenic and fetal toxicity studies show no harmful effect, but advised not to use it in pregnancy, especially during the 1st trimester. Safety during lactation not established yet.
Precautions & Warnings
Boxol should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.
Therapeutic Class
Cough expectorants & mucolytics
Storage Conditions
Protect from direct light exposure, Store in a dry place at a temperature not exceeding 30°C, Keep out of the reach of children