Broxolin 15 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ambroxol hydrochloride |
| Company | Jayson pharmaceuticals ltd |
Indications
- Productive cough
- Acute and chronic inflammatory disorders of upper and lower respiratory tracts
- Inflammatory disease of rhinopharyngeal tract
- Asthmatic bronchitis
- Bronchiectasis
- Chronic pneumonia
Pharmacology
Ambroxol is the active metabolite of bromhexine, possessing a greater bronchosecretolytic effect. It improves sputum rheology by hydrating mechanism leading to liquefaction of mucus in the respiratory tract, stimulating production of phospholipids of surfactant, reducing bronchial hyperactivity, and having anti-inflammatory properties. In patients with COPD, it improves airway patency.
Dosage & Administration
- Average daily dose (preferably after meal):
- Pediatric Drops: 0-6 months: 0.5 ml 2 times a day, 6-12 months: 1 ml 2 times a day, 1-2 years: 1.25 ml 2 times a day
- Syrup: 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day, 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day, 10 years and adults: 10 ml (2 teaspoonful) 3 times a day
- Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily
Interaction
Broxolin should not be taken simultaneously with antitussives (e.g. Codeine) because phlegm, which has been liquefied by Broxolin might not be expectorated.
Contraindications
Known hypersensitivity to Ambroxol or Bromhexine.
Side Effects
Gastrointestinal side effects like epigastric pain, stomach overfill feeling may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema have been reported.
Pregnancy & Lactation
Teratogenic and fetal toxicity studies have shown no harmful effect of Ambroxol. However, it is advised not to use it in pregnancy, especially during the 1st trimester. Safety during lactation has not been established yet.
Precautions & Warnings
Broxolin should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.
Therapeutic Class
Cough expectorants & mucolytics
Storage Conditions
Protect from direct light exposure, Store in a dry place at a temperature not exceeding 30°C, Keep out of the reach of children.