Hybrox 6 mg/ml (Pediatric Drops)

15 ml bottle: ৳ 30.09

Medicine Details

Indications

  • Productive cough
  • Acute and chronic inflammatory disorders of upper and lower respiratory tracts
  • Inflammatory disease of rhinopharyngeal tract
  • Asthmatic bronchitis with thick expectoration
  • Bronchiectasis
  • Chronic pneumonia

Pharmacology

  • Greater bronchosecretolytic effect than bromhexine
  • Improves sputum rheology by hydrating mechanism
  • Liquefaction of mucus in the lumen of respiratory tract
  • Facilitates expectoration of mucus
  • Reduces dyspnea
  • Stimulates production of phospholipids of surfactant by alveolar cells
  • Contributes to the lowering of superficial tension in the alveoli
  • Reduces bronchial hyperactivity
  • Has anti-inflammatory properties
  • Improves airway patency in patients with COPD

Dosage & Administration

  • Average daily dose preferably after a meal
  • Pediatric drops for different age groups
  • Syrup for different age groups
  • Sustained release capsule dosage for adults and children over 12 years old

Interaction

  • Should not be taken simultaneously with antitussives
  • Phlegm liquefied by Hybrox might not be expectorated if taken with antitussives

Contraindications

  • Known hypersensitivity to Ambroxol or Bromhexine

Side Effects

  • Gastrointestinal side effects like epigastric pain, stomach overfill feeling
  • Occasional occurrence of gastrointestinal side effects
  • Rare allergic responses like eruption, urticaria, or angioneurotic edema

Pregnancy & Lactation

  • Teratogenic and fetal toxicity studies showed no harmful effect of Ambroxol
  • Advised not to use it in pregnancy, especially during the 1st trimester
  • Safety during lactation not established yet

Precautions & Warnings

  • Give cautiously to patients with gastric and duodenal ulceration or convulsive disorders
  • Patients with hepatic and renal insufficiency should take it with caution

Therapeutic Class

  • Cough expectorants & mucolytics

Storage Conditions

  • Protect from direct light exposure
  • Store in a dry place at a temperature not exceeding 30°C
  • Keep out of the reach of children

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