Carbolin DS 250 mg/5 ml (Syrup)

100 ml bottle: ৳ 40.00

Medicine Details

Category Details
Generic Carbocisteine
Company Eskayef pharmaceuticals ltd
Also available as

Indications

  • Expectoration in upper respiratory inflammation (pharyngitis, laryngitis)
  • Expectoration in acute bronchitis
  • Expectoration in bronchial asthma
  • Expectoration in chronic bronchitis
  • Expectoration in bronchiectasis
  • Expectoration in pulmonary tuberculosis
  • Drainage in chronic sinusitis
  • Drainage in otitis media with effusion

Pharmacology

  • Reduces viscosity of non-infected secretions from mucous cells in the respiratory tract
  • Breaks disulphide bonds which cross-link certain glycoprotein molecules present in the mucus
  • Alters local ionic charges affecting the viscosity of mucus
  • Alters the composition of mucin secreted by the respiratory mucosa

Dosage & Administration

  • Initial dosage of 2250 mg daily in divided doses for adults
  • Reduced to 1500 mg daily in divided doses when a satisfactory response has been obtained
  • Normal daily dose is 20 mg/kg body weight in divided doses for children
  • 62.5-125 mg 4 times daily for 2-5 years old
  • 250 mg 3 times daily for 6-12 years old

Interaction

  • No hazardous or therapeutically useful interactions reported

Contraindications

  • Contraindicated in active peptic ulceration and in patients with hypersensitivity to the drug

Side Effects

  • Gastrointestinal discomfort
  • Nausea
  • Diarrhoea
  • Gastrointestinal bleeding
  • Headache
  • Skin rash

Pregnancy & Lactation

  • Not recommended in the first trimester of pregnancy
  • No information available on the use of carbocisteine during lactation

Precautions & Warnings

  • Use with caution in patients with a recent history of peptic ulcer and recurrent gastrointestinal bleeding

Therapeutic Class

  • Cough expectorants & mucolytics

Storage Conditions

  • Keep below 30°C temperature, away from light & moisture, Keep out of the reach of children

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