Cophilex (30 mg+100 mg+1.25 mg)/5 ml (Syrup)

100 ml bottle: ৳ 55.00

Medicine Details

Indications

  • Symptomatic relief of upper respiratory tract disorders
  • Productive cough relief
  • Nasal decongestant administration
  • Histamine H1 receptor antagonist administration
  • Expectorant combination

Pharmacology

  • Pseudoephedrine - decongestant and bronchodilator
  • Guaifenesin - reduces viscosity of sputum
  • Triprolidine - antihistamine

Dosage & Administration

  • Adult dosage: 10 ml (2 teaspoonful) three times a day
  • Children 6-12 years dosage: 5 ml (1 teaspoonful) three times a day
  • Children 2-5 years dosage: 2.5 ml (1/2 teaspoonful) three times a day
  • Consult physician for children under 2 years

Interaction

  • Concomitant use with sympathomimetic agents
  • Potential rise in blood pressure
  • Partially reverses hypotensive action of certain drugs

Contraindications

  • Known hypersensitivity to any constituents
  • Cardiovascular disease including hypertension
  • Lower respiratory symptoms including asthma
  • Monoamine oxidase inhibitor (MAOI) therapy

Side Effects

  • CNS depression or excitation
  • Drowsiness
  • Sleep disturbances
  • Hallucinations
  • Skin rashes
  • Tachycardia
  • Dryness of mouth, nose and throat

Pregnancy & Lactation

  • Caution in pregnancy
  • Balance potential benefits with possible hazards to fetus

Precautions & Warnings

  • May cause drowsiness
  • Avoid driving or operating machinery
  • Avoid concomitant alcohol or sedatives
  • Use with caution in hypertension, heart disease, diabetes, hyperthyroidism, elevated intra-ocular pressure, prostatic enlargement, severe renal and hepatic impairment
  • Avoid use in persistent or chronic cough without physician's direction

Overdose Effects

  • Drowsiness
  • Irritability
  • Restlessness
  • Lethargy
  • Dizziness
  • Gastrointestinal discomfort
  • Respiratory depression
  • Convulsion
  • Tremor
  • Tachycardia
  • Hypertension
  • Support respiration and control convulsion in case of overdose
  • Consider gastric lavage and bladder catheterization if indicated

Therapeutic Class

  • Combined cough expectorants

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Do not refrigerate

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