E-Cof (30 mg+100 mg+1.25 mg)/5 ml (Syrup)
100 ml bottle: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pseudoephedrine guaiphenasine triprolidine |
| Company | Edruc limited |
Indications
- Symptomatic relief of upper respiratory tract disorders
- Productive cough relief
- Nasal decongestant
- Histamine H1 receptor antagonist
- Expectorant combination
Pharmacology
- Decongestant
- Bronchodilator
- Vasoconstriction
- Bronchial relaxation
- Increased heart rate and contractility
- Norepinephrine release
- Antihistamine
- Relieves hypersensitivity reactions
Dosage & Administration
- Recommended dosage for adults
- Recommended dosage for children over 12 years
- Recommended dosage for children 6-12 years
- Recommended dosage for children 2-5 years
- Physician's advice for children under 2 years
Interaction
- Contraindicated with sympathomimetic agents
- Interference with monoamine oxidase inhibitors
- Partial reversal of hypotensive action of certain drugs
Contraindications
- Known hypersensitivity to constituents
- Cardiovascular disease including hypertension
- Lower respiratory symptoms including asthma
- Monoamine oxidase inhibitor (MAOI) therapy
Side Effects
- CNS depression or excitation
- Drowsiness
- Sleep disturbances
- Hallucinations
- Skin rashes
- Tachycardia
- Dryness of mouth, nose and throat
Pregnancy & Lactation
- Caution in pregnancy and lactation
- Balancing potential benefits against possible hazards to the developing fetus
Precautions & Warnings
- Potential drowsiness
- Advice against driving or operating machinery
- Avoid concomitant administration with alcohol or sedatives
- Caution in patients with mild to moderate hypertension
- Caution in hypertension and heart disease, diabetes, hyperthyroidism, elevated intra-ocular pressure, prostatic enlargement, renal and hepatic impairment
- Avoid use for persistent or chronic cough without physician's direction
Overdose Effects
- Acute toxicity effects
- Respiratory depression
- Convulsion
- Tachycardia
- Hypertension
- Necessary supportive measures
- Gastric lavage may be indicated
- Bladder catheterization may be necessary
Therapeutic Class
- Combined cough expectorants
Storage Conditions
- Store below 25°C
- Protect from light
- Do not refrigerate
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