Expoten (30 mg+100 mg+1.25 mg)/5 ml (Syrup)
100 ml bottle: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pseudoephedrine guaiphenasine triprolidine |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Symptomatic relief of upper respiratory tract disorders
- Productive cough relief
- Relief of nasal decongestant
- Histamine H1 receptor antagonist
- Expectorant combination
Pharmacological Actions
- Decongestant
- Bronchodilator
- Vasoconstriction via stimulation of adrenergic receptors
- Bronchial relaxation
- Increase in heart rate and contractility
- Norepinephrine release
- Reduction of sputum viscosity
- Antihistamine action
Dosage and Administration
- Adult dosage: 10 ml (2 teaspoonful) three times a day
- Children 6-12 years dosage: 5 ml (1 teaspoonful) three times a day
- Children 2-5 years dosage: 2.5 ml (1/2 teaspoonful) three times a day
- Prefer physician's advice for children under 2 years
Interactions
- Concurrent use with sympathomimetic agents may cause rise in blood pressure
- Partial reversal of hypotensive action of certain drugs
Contraindications
- Known hypersensitivity to constituents
- Cardiovascular disease including hypertension
- Lower respiratory symptoms including asthma
- Monoamine oxidase inhibitor (MAOI) therapy
Side Effects
- CNS depression or excitation
- Drowsiness
- Sleep disturbances
- Hallucinations
- Skin rashes
- Tachycardia
- Dryness of mouth, nose and throat
Pregnancy and Lactation
- Caution should be exercised during pregnancy
- Balancing potential benefits against possible hazards to the fetus
Precautions and Warnings
- May cause drowsiness
- Advised not to drive or operate machinery
- Avoid concomitant administration with alcohol or sedatives
- Caution in patients with hypertension and heart disease
- Caution in patients with diabetes, hyperthyroidism, elevated intra-ocular pressure, prostatic enlargement, severe renal and hepatic impairment
- Avoid use for persistent or chronic cough without physician direction
Overdose Effects
- Drowsiness
- Irritability
- Restlessness
- Lethargy
- Dizziness
- Gastrointestinal discomfort
- Respiratory depression
- Convulsion
- Tremor
- Hypertension
- Necessary measures to maintain respiration and control convulsions
- Gastric lavage may be necessary
- Catheterization of bladder may be necessary
Therapeutic Class
Combined cough expectorants
Storage Conditions
Store below 25°C, Protect from light, Do not refrigerate
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