Koftex (30 mg+100 mg+1.25 mg)/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Indications

  • Symptomatic relief of upper respiratory tract disorders
  • Productive cough relief
  • Nasal decongestant
  • Histamine H1 receptor antagonist
  • Expectorant combination

Pharmacology

  • Pseudoephedrine as a decongestant and bronchodilator
  • Pseudoephedrine mechanism of action
  • Guaifenesin as an expectorant
  • Triprolidine as an antihistamine

Dosage & Administration

  • Adult dosage
  • Children dosage
  • Physician's advice for children under 2 years

Interaction

  • Concomitant use with sympathomimetic agents
  • Interaction with monoamine oxidase inhibitors
  • Partially reversing hypotensive action of certain drugs

Contraindications

  • Known hypersensitivity to constituents
  • Cardiovascular disease including hypertension
  • Lower respiratory symptoms including asthma
  • Monoamine oxidase inhibitor (MAOI) therapy

Side Effects

  • CNS depression or excitation
  • Drowsiness
  • Sleep disturbances
  • Hallucinations
  • Skin rashes
  • Tachycardia
  • Dryness of mouth, nose, and throat

Pregnancy & Lactation

  • Caution in pregnancy & lactation
  • Balancing potential benefits against possible hazards to the fetus

Precautions & Warnings

  • Potential drowsiness
  • Avoiding driving or operating machinery
  • Avoiding alcohol or other centrally acting sedatives
  • Caution in patients suffering from mild to moderate hypertension
  • Caution in various disease conditions
  • Use in persistent or chronic cough only if directed by a physician

Overdose Effects

  • Acute toxicity effects
  • Necessary measures for supporting respiration and controlling convulsion
  • Indications for gastric lavage and catheterization of bladder

Therapeutic Class

  • Combined cough expectorants

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Do not refrigerate

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