Smile (30 mg+100 mg+1.25 mg)/5 ml (Syrup)

100 ml bottle: ৳ 35.00

Medicine Details

Indications

  • Symptomatic relief of upper respiratory tract disorders
  • Productive cough relief
  • Nasal decongestant administration
  • Histamine H1 receptor antagonist
  • Expectorant combination

Pharmacology

  • Pseudoephedrine as decongestant and bronchodilator
  • Alpha-adrenergic receptor agonist
  • Beta-adrenergic receptor agonist
  • Norepinephrine release stimulation
  • Guaifenesin as expectorant
  • Reduction of sputum viscosity
  • Increase in respiratory tract hydration
  • Triprolidine as antihistamine
  • Relief of hypersensitivity reactions

Dosage & Administration

  • Adult dosage: 10 ml (2 teaspoonful) three times a day
  • Children dosage: 5-10 ml three times a day
  • Physician's advice for children under 2 years

Interaction

  • Concomitant use with sympathomimetic agents
  • Potential rise in blood pressure
  • Reversal of hypotensive action of certain drugs

Contraindications

  • Hypersensitivity to constituents
  • Cardiovascular disease
  • Lower respiratory symptoms
  • Monoamine oxidase inhibitor (MAOI) therapy

Side Effects

  • CNS depression or excitation
  • Drowsiness
  • Sleep disturbances
  • Hallucinations
  • Skin rashes with or without irritation
  • Tachycardia
  • Dryness of mouth, nose and throat

Pregnancy & Lactation

  • Caution in pregnancy and lactation
  • Balance of potential benefits against possible hazards

Precautions & Warnings

  • Potential drowsiness
  • Avoid driving or operating machinery
  • Avoid concomitant administration with alcohol or sedatives
  • Caution in mild to moderate hypertension
  • Caution in specific disease conditions
  • Avoid use for persistent or chronic cough without physician's direction

Overdose Effects

  • Drowsiness
  • Irritability
  • Restlessness
  • Lethargy
  • Dizziness
  • Gastrointestinal discomfort
  • Respiratory depression
  • Convulsion
  • Tremor
  • Tachycardia
  • Hypertension
  • Acute toxicity effects
  • Necessary measures for overdose

Therapeutic Class

  • Combined cough expectorants

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Do not refrigerate

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