Triphen (30 mg+100 mg+1.25 mg)/5 ml (Syrup)
100 ml bottle: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pseudoephedrine guaiphenasine triprolidine |
| Company | Doctors chemical works ltd |
Indications
- Symptomatic relief of upper respiratory tract disorders
- Productive cough relief
- Nasal decongestant
- Histamine H1 receptor antagonist
- Expectorant combination
Pharmacology
- Pseudoephedrine as decongestant
- Pseudoephedrine as bronchodilator
- Pseudoephedrine as α-adrenergic receptor agonist
- Pseudoephedrine as β-adrenergic receptor agonist
- Pseudoephedrine causing vasoconstriction
- Pseudoephedrine causing bronchial relaxation
- Pseudoephedrine releasing norepinephrine
- Guaifenesin as expectorant
- Guaifenesin reducing viscosity of sputum
- Guaifenesin increasing hydration of respiratory tract
- Triprolidine as antihistamine
- Triprolidine for relief of hypersensitivity reactions
Dosage & Administration
- Adult dosage: 10 ml (2 teaspoonful) three times a day
- Children over 12 years dosage: 10 ml (2 teaspoonful) three times a day
- Children 6-12 years dosage: 5 ml (1 teaspoonful) three times a day
- Children 2-5 years dosage: 2.5 ml (1/2 teaspoonful) three times a day
- Prefer physician’s advice for children aged less than 2 years
Interaction
- Concomitant use of sympathomimetic agents
- Rise in blood pressure potential
Contraindications
- Known hypersensitivity to constituents
- Cardiovascular disease including hypertension
- Lower respiratory symptoms including asthma
- Monoamine oxidase inhibitor (MAOI) therapy
Side Effects
- CNS depression or excitation
- Drowsiness
- Sleep disturbances
- Hallucinations
- Skin rashes with or without irritation
- Tachycardia
- Dryness of mouth, nose and throat
Pregnancy & Lactation
- Limited data on use during pregnancy
- Balancing potential benefits against possible hazards to the fetus
Precautions & Warnings
- Potential drowsiness
- Avoiding driving or operating machinery if affected
- Avoiding concomitant administration of alcohol or other sedatives
- Caution in patients with mild to moderate hypertension
- Exercise caution in hypertension, heart disease, diabetes, hyperthyroidism, elevated intra-ocular pressure, prostatic enlargement, severe renal and hepatic impairment
Overdose Effects
- Acute toxicity effects
- Drowsiness
- Irritability
- Restlessness
- Lethargy
- Dizziness
- Gastrointestinal discomfort
- Respiratory depression
- Convulsion
- Tremor
- Tachycardia
- Hypertension
- Measures to maintain and support respiration
- Control of convulsion
- Gastric lavage
- Catheterization of bladder
Therapeutic Class
- Combined cough expectorants
Storage Conditions
- Store below 25° C
- Protect from light
- Do not refrigerate
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