Nikethamide 250 mg/ml (Injection)
2 ml ampoule: ৳ 12.04 (2 x 5: ৳ 120.40)
Medicine Details
| Category | Details |
|---|---|
| Generic | Nikethamide |
| Company | Jayson pharmaceuticals ltd |
Indications
- Central nervous system stimulant
- Barbiturate overdose
Pharmacology
- Formerly used as a respiratory stimulant
- Effective doses close to toxic effects
Dosage & Administration
- 1500 mg as single dose
- Frequency as recommended
Interaction
- Additive pressor effects with sympathomimetics or MAOIs
- Increased risk of cardiac arrythmias with some anaesthetics
- May mask the effects of neuromuscular blockers
- Increased risk of convulsions with bupropion
Contraindications
- Porphyria
- Epilepsy or other convulsive disorders
- Cerebral edema
- Cerebrovascular accident
- Head injury
- Acute severe asthma
- Physical obstruction of the airway
- Severe hypertension
- Ischaemic heart disease
- Hyperthyroidism
- Phaeochromocytoma
Side Effects
- Skin irritation
- Eye irritation
- Respiratory irritation
Precautions & Warnings
- Less severe degrees of hypertension or impaired cardiac reserve
- Liver dysfunction
Therapeutic Class
- Respiratory stimulants: analeptics