Anquil 7.5 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
Category | Details |
---|---|
Generic | Midazolam |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Short-term treatment of insomnia
- Sedation in premedication before surgical or diagnostic procedures
Description
- Sleep-inducing agent
- Rapid onset
- Short duration of action
- Anxiolytic effect
- Anticonvulsant effect
- Muscle-relaxant effect
Pharmacology
- Actions mediated through inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Increase of GABA activity
- Sedating effect
- Muscle relaxation
- Sleep induction
- Anesthesia
- Amnesia
Dosage & Administration
- Oral dosage for adults: 7.5-15 mg daily
- Initial intravenous dose for endoscopic or cardiovascular procedures: approximately 2.5 mg in healthy adults
- Intramuscular dose for adults: 0.07-0.1 mg/kg body weight
- Rectal administration in children for preoperative sedation
Interaction
- Enhancement of central sedative effect of various drugs such as neuroleptics, antidepressants, analgesics, anesthetics
Contraindications
- Severe respiratory insufficiency
- Severe hepatic insufficiency
- Myasthenia gravis
- Sleep apnea syndrome
- Hypersensitivity to benzodiazepines
Side Effects
- Drowsiness
- Confusion
- Fatigue
- Headache
- Muscle weakness
- Fluctuations in vital signs
- Respiratory depression
- Apnea
- Variations in blood pressure
- Pulse rate variations
Pregnancy & Lactation
- Avoidance during pregnancy unless no safer alternative
- Passes into breast milk
Precautions & Warnings
- Very slow IV administration
Overdose Effects
- Coma
- Areflexia
- Cardiorespiratory depression
- Apnea
- Controlled with benzodiazepine antagonist flumazenil
Therapeutic Class
- Benzodiazepine hypnotics
- Benzodiazepine sedatives
Storage Conditions
- Protection from light and moisture
- Cool and dry place
- Keep out of the reach of children
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