Anquil 7.5 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Short-term treatment of insomnia
  • Sedation in premedication before surgical or diagnostic procedures

Description

  • Sleep-inducing agent
  • Rapid onset
  • Short duration of action
  • Anxiolytic effect
  • Anticonvulsant effect
  • Muscle-relaxant effect

Pharmacology

  • Actions mediated through inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Increase of GABA activity
  • Sedating effect
  • Muscle relaxation
  • Sleep induction
  • Anesthesia
  • Amnesia

Dosage & Administration

  • Oral dosage for adults: 7.5-15 mg daily
  • Initial intravenous dose for endoscopic or cardiovascular procedures: approximately 2.5 mg in healthy adults
  • Intramuscular dose for adults: 0.07-0.1 mg/kg body weight
  • Rectal administration in children for preoperative sedation

Interaction

  • Enhancement of central sedative effect of various drugs such as neuroleptics, antidepressants, analgesics, anesthetics

Contraindications

  • Severe respiratory insufficiency
  • Severe hepatic insufficiency
  • Myasthenia gravis
  • Sleep apnea syndrome
  • Hypersensitivity to benzodiazepines

Side Effects

  • Drowsiness
  • Confusion
  • Fatigue
  • Headache
  • Muscle weakness
  • Fluctuations in vital signs
  • Respiratory depression
  • Apnea
  • Variations in blood pressure
  • Pulse rate variations

Pregnancy & Lactation

  • Avoidance during pregnancy unless no safer alternative
  • Passes into breast milk

Precautions & Warnings

  • Very slow IV administration

Overdose Effects

  • Coma
  • Areflexia
  • Cardiorespiratory depression
  • Apnea
  • Controlled with benzodiazepine antagonist flumazenil

Therapeutic Class

  • Benzodiazepine hypnotics
  • Benzodiazepine sedatives

Storage Conditions

  • Protection from light and moisture
  • Cool and dry place
  • Keep out of the reach of children

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