Hypnocum 7.5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Midazolam |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Short-term treatment of insomnia
- Sedation in premedication before surgical or diagnostic procedures
Description
A sleep-inducing agent characterized by rapid onset and short duration of action. It also exerts an anxiolytic, anticonvulsant, and muscle-relaxant effect
Pharmacology
Benzodiazepines increase the activity of GABA, thereby producing a sedating effect, relaxing skeletal muscles, and inducing sleep, anesthesia, and amnesia
Dosage & Administration
- Oral dosage for adults: 7.5-15 mg daily
- Intravenous administration for endoscopic or cardiovascular procedures: initial dose in healthy adults is approximately 2.5 mg
- Intramuscular administration for adults: 0.07-0.1 mg/kg body weight
Interaction
Hypnocum can enhance the central sedative effect of neuroleptics, tranquillizers, antidepressants, sleep-inducing drugs, analgesics, anaesthetics, antipsychotics, anxiolytics, antiepileptic drugs, and sedative antihistamines
Contraindications
- Severe respiratory insufficiency
- Severe hepatic insufficiency
- Myasthenia gravis
- Sleep apnea syndrome
- Known hypersensitivity to benzodiazepines or any component of the product
Side Effects
- Drowsiness during daytime
- Confusion
- Fatigue
- Headache
- Muscle weakness
- Fluctuations in vital signs including respiratory depression, apnea, variations in blood pressure and pulse rate following parenteral administration
Pregnancy & Lactation
Midazolam should be avoided during pregnancy unless there is no safer alternative. It should not be administered to breastfeeding mothers.
Precautions & Warnings
Hypnocum IV should be administered very slowly
Overdose Effects
Extreme overdosage may lead to coma, areflexia, cardiorespiratory depression, and apnea. Overdosage effects can be controlled with benzodiazepine antagonist flumazenil
Therapeutic Class
- Benzodiazepine hypnotics
- Benzodiazepine sedatives
Storage Conditions
Protect from light and moisture, store in cool and dry place. Keep out of the reach of children