Midolam 7.5 mg (Tablet)

Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30

Medicine Details

Category Details
Generic Midazolam
Company Opsonin pharma ltd
Also available as
Midolam 15 mg tablet Midolam 5 mg injection Midolam 15 mg injection

Indications

  • Short-term treatment of insomnia
  • Sedation in premedication before surgical or diagnostic procedures

Description

Sleep-inducing agent characterized by rapid onset and short duration of action. Exhibits anxiolytic, anticonvulsant, and muscle-relaxant effects

Pharmacology

Mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Increases GABA activity, producing sedating effect, relaxing skeletal muscles, inducing sleep, anesthesia, and amnesia

Dosage & Administration

  • Oral dosage for adults: 7.5-15 mg daily
  • Oral dosage in elderly and debilitated patients: 7.5 mg
  • Oral dosage for premedication: 15 mg 30-60 minutes before the procedure
  • Intravenous administration dose for endoscopic or cardiovascular procedures in healthy adults: approximately 2.5 mg
  • Intramuscular administration for adults: 0.07-0.1 mg/kg body weight
  • Rectal administration in children for preoperative sedation: 0.35-0.45 mg/kg 20-30 min before induction of general anesthesia

Interaction

Enhances the central sedative effect of neuroleptics, tranquillizers, antidepressants, sleep-inducing drugs, analgesics, anaesthetics, antipsychotics, anxiolytics, antiepileptic drugs, and sedative antihistamines

Contraindications

Severe respiratory or hepatic insufficiency, myasthenia gravis, sleep apnea syndrome, known hypersensitivity to benzodiazepines or any component of the product

Side Effects

  • Drowsiness, confusion, fatigue, headache, and muscle weakness at the start of therapy
  • Parenteral administration may cause respiratory depression, apnea, variations in blood pressure, and pulse rate

Pregnancy & Lactation

Avoid during pregnancy unless no safer alternative. Avoid in breastfeeding mothers as it passes into breast milk

Precautions & Warnings

Administer IV very slowly

Overdose Effects

May lead to coma, areflexia, cardiorespiratory depression, and apnea. Can be controlled with benzodiazepine antagonist flumazenil

Therapeutic Class

  • Benzodiazepine hypnotics
  • Benzodiazepine sedatives

Storage Conditions

Protect from light and moisture. Store in a cool and dry place. Keep out of the reach of children

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