Bonemass D 70 mg+2800 IU (Tablet)

Indications

• Treatment of osteoporosis in postmenopausal women
• Treatment of osteoporosis in men
• Increases bone mass and reduces fractures

Pharmacology

• Alendronate Sodium acts as a specific inhibitor of osteoclast mediated bone resorption
• Requires administration at least 30 minutes before breakfast
• Shows preferential localization to sites of bone resorption

Dosage

• Recommended dosage for postmenopausal women
• Recommended dosage for men with osteoporosis

Administration

• Must be taken at least 30 minutes before the first food, beverage, or medication of the day
• Should be swallowed with a full glass of water upon rising for the day

Interaction

• Calcium supplement, antacids, and some oral medications interfere with absorption
• NSAID and aspirin interaction
• Impact of mineral oils, orlistat, and bile acid sequestrants on vitamin D absorption

Contraindications

• Abnormalities of the esophagus
• Inability to stand or sit upright for at least 30 minutes
• Hypersensitivity to any component
• Hypocalcaemia

Side Effects

• Esophageal reactions
• Abdominal pain and distension
• Diarrhea or constipation
• Musculoskeletal pain
• Headache
• Rash and erythema
• Transient decreases in serum calcium and phosphate

Pregnancy & Lactation

• Pregnancy category C
• Caution during pregnancy and lactation

Precautions & Warnings

• Correction of hypocalcaemia and mineral metabolism disturbances
• Local irritation of upper gastrointestinal mucosa
• Caution for patients with active upper gastrointestinal problems

Use in Special Populations

• No dosage adjustment for the elderly or mild-to-moderate renal insufficiency
• Not recommended for severe renal insufficiency

Overdose Effects

• Hypocalcemia and hypophosphatemia
• Upper gastrointestinal adverse events
• Signs and symptoms of vitamin D toxicity

Therapeutic Class

• Inhibiting bone resorption

Storage Conditions

• Store in a cool and dry place
• Protect from light and moisture
• Keep out of the reach of children

Related Brands

• Ostel-D 70 mg+2800 IU (Tablet) - square-pharmaceuticals-plc