Sedapen 5 mg (Tablet)
Unit Price: ৳ 0.69 (100's pack: ৳ 69.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diazepam |
| Company | Amico laboratories ltd |
Product Title
- Sedapen - Benzodiazepine Tranquillizer
Category
- Anxiety Medication
- Benzodiazepine Derivative
- Tranquillizer
- Anticonvulsant Medication
Description
- Safe tranquillizer with anxiolytic, anticonvulsant, and central muscle relaxant actions
Indications
- Short-term treatment of mild to moderate anxiety
- Treatment of excitation, agitation, fear, aggressiveness
- Anxiety reactions from stressed conditions
- Anxiety states with somatic expression
- Treatment of acute alcohol withdrawal
- Control of status epilepticus
- Premedication for surgical procedures
- Treatment of febrile convulsions
- Insomnia of hospitalized patients
Pharmacology
- Binds to specific site on the GABA receptor
- Potentiates the effect of GABA
- Opens chloride ion channels into cells
- Rapid and complete absorption after oral administration
- Peak plasma concentration reached within 15-90 minutes
- Mean plasma half-life of 30 hours
- Metabolized in the liver
- Excreted in urine and feces
- Significant absorption after rectal administration
Dosage & Administration
- Oral administration for anxiety, insomnia, and night terrors in children
- IM/slow IV injection for severe acute anxiety, panic attacks, and febrile convulsion in children
- Rectal administration in case of children
- Specific doses for different conditions and age groups
Interaction
- Not recommended with alcohol
- Potential interaction with neuroleptics, hypnotics, sedative antihistamines, CNS depressants, general anesthetics, narcotic analgesics, antidepressants, phonobarbitone, cimetidine, omeprazole, and isoniazide
Contraindications
- Myasthenia gravis
- Pulmonary insufficiency
- Respiratory depression
- Hypersensitivity to benzodiazepine
Side Effects
- Somnolence
- Dizziness
- Lightheadedness
- Confusion
- Ataxia
Pregnancy & Lactation
- Crosses placental barrier
- Passes into breast milk
- Avoidable during pregnancy and lactation
- US FDA pregnancy category D
Precautions & Warnings
- Avoid prolonged use
- Avoid abrupt withdrawal
- Use with caution in respiratory disease, muscle weakness, history of drug or alcohol abuse, hepatic or renal impairment
Overdose Effects
- Sedation
- Muscle weakness
- Profound sleep or paradoxical excitation
- Ataxia
- Hypotonia
- Hypotension
- Respiratory depression
- Rarely coma and death
Therapeutic Class
- Benzodiazepine sedatives
- Centrally acting skeletal muscle relaxants
- Primary anti-epileptic drugs
Storage Conditions
- Store in a cool and dry place below 25˚C temperature, protected from light