Sedil 10 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 7.00 (2 x 5: ৳ 70.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diazepam |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Short-term treatment of anxiety
- Treatment of excitation and agitation
- Management of fear and aggressiveness
- Anxiety reactions caused by stress
- Management of acute alcohol withdrawal
- Premedication for surgical procedures
- Management of insomnia
Description
- Benzodiazepine derivative
- Tranquillizer with anxiolytic and anticonvulsant actions
Pharmacology
- Attaches to GABA receptor
- Potentiates the effect of GABA
- Rapid absorption after oral administration
- Metabolized in the liver
Dosage & Administration
- Oral administration for anxiety and insomnia
- IM/slow IV injection for acute anxiety and febrile convulsions
- Rectal administration for children
- Elderly dose adjustment
Interaction
- Interaction with alcohol and CNS depressants
- Effect of concomitant use of medications on Sedil clearance
Contraindications
- Myasthenia gravis
- Pulmonary insufficiency
- Respiratory depression
- Hypersensitivity to benzodiazepine
Side Effects
- Somnolence
- Dizziness
- Confusion
- Ataxia
- Light-headedness
Pregnancy & Lactation
- Crosses placental barrier
- Passes into breast milk
- US FDA pregnancy category D
Precautions & Warnings
- Prolonged use and abrupt withdrawal should be avoided
- Caution in respiratory disease and muscle weakness
- History of drug or alcohol abuse
- Hepatic or renal impairment
Overdose Effects
- Sedation
- Muscle weakness
- Respiratory depression
- Coma
- Death
Therapeutic Class
- Benzodiazepine sedatives
- Centrally acting skeletal muscle relaxants
- Primary anti-epileptic drugs
Storage Conditions
- Cool and dry place protected from light