Colax 10 mg (Tablet)
Unit Price: ৳ 2.74 (50's pack: ৳ 137.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobazam |
| Company | Pharmadesh laboratories ltd |
Indications
- Acute and chronic anxiety states
- Restlessness
- Irritability
- Sleep disturbances
- Emotional instability
- Depression treatment
- Adjunctive therapy in schizophrenia
- Adjunctive therapy in epilepsy
Pharmacology
- Binds to distinct binding sites
- Increased GABA receptor activity
- Hyperpolarization and membrane stabilization
Dosage
- Adjustable to indication and severity
- Recommended initial dose for adults and adolescents
- Recommended initial dose for elderly
- Recommended initial dose for children
- Secondary dosage adjustment
- Recommended timing of doses
- Duration of treatment guidelines
- Discontinuation of treatment guidelines
Administration
- Can be administered whole or crushed
- Divisible tablets
- Can be taken with or without food
Interaction
- Alcohol interaction
- Interaction with CNS depressants
- Opioids interaction
- Interaction with anticonvulsants
- Interaction with narcotic analgesics
- Muscle relaxants interaction
- CYP 2C19 inhibitors interaction
- CYP 2D6 substrates interaction
Contraindications
- Hypersensitivity
- Myasthenia gravis
- Severe respiratory insufficiency
- Sleep apnoea syndrome
- Severe impairment of liver function
- Breastfeeding
- Use in children between 6 months and 3 years
Side Effects
- Decreased appetite
- Irritability
- Aggression
- Restlessness
- Somnolence
- Sedation
- Dizziness
- Disturbance in attention
- Dry mouth
- Nausea
- Rash
- Muscle spasms
Pregnancy & Lactation
- Not recommended during first trimester
- Potential risk to the fetus
- Passes into breast milk
Precautions & Warnings
- Serious skin reactions
- Respiratory depression
- Muscle weakness
- Renal and hepatic impairment
- Elderly patients sensitivity
- Tolerance in epilepsy
- CYP2C19 poor metabolizers impact
- Suicidality risk
- Concomitant use of CYP2C19 inhibitors
Therapeutic Class
- Benzodiazepine hypnotics
Storage Conditions
- Do not use after expiry date
- Store below 30°C
- Protect from light
- Keep out of the reach of children