Sizonil 1 mg (Tablet)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)

Strip Price: ৳ 20.00

Medicine Details

Category	Details
Generic	Trifluoperazine
Company	Healthcare pharmaceuticals ltd
Also available as	Sizonil 5 mg tablet

Title

Sizonil Tablet

Description

Sizonil Tablet is indicated for anxiety states, nausea and vomiting, psychotic disorders, and is part of the phenothiazine class of compounds with antagonistic action at dopamine receptors in the CNS. The dosage for various conditions depends on age, with precautions for elderly and those with cardiovascular diseases. The medicine should be stored at room temperature away from light and moisture.

Dimensions

N/A

Color Options

N/A

Functions

Controls excessive anxiety
Prevents nausea and vomiting
Manages psychotic disorders

Materials

Phenothiazine compounds

Technical Specifications

Antagonism at dopamine receptors in the CNS
Management of psychotic disorders like schizophrenia

Design Elements

N/A

Usability Features

Dosage adjustments for different age groups
Storage at room temperature

Dosage & Administration

Recommended starting dose for adults and child over 12 years is 2-5 mg b.i.d, with gradual increases
Dosage adjustment for children depending on weight and symptoms severity
Reduced initial dose for the elderly
Different dosages for short-term management of severe anxiety and antiemetic purposes

Interaction

Diminishes effect of oral anticoagulants
Increased plasma levels when administered with propranolol

Contraindications

Comatose patients
Existing blood dyscrasias
Known liver damage
Hypersensitivity to active ingredient or related compounds

Side Effects

Transient restlessness
Dystonias or parkinsonism-like symptoms
CNS reactions like drowsiness, dizziness, fatigue, blurred vision, seizures
Peripheral oedema, blood dyscrasias, jaundice may occasionally occur
Tachycardia, constipation, urinary hesitancy and retention, hyperpyrexia reported very rarely

Pregnancy & Lactation

Safety not established during pregnancy
Potential benefits should outweigh possible hazards
Reported instances of adverse effects in newborns whose mothers received phenothiazines
Adequate human data not available for lactation

Precautions & Warnings

Reduced initial dosage for elderly patients
Specially sensitive elderly patients, particularly to extra pyramidal and hypotensive effects
Caution in patients with cardiovascular disease including arrhythmias and angina pectoris

Overdose Effects

Predominantly extrapyramidal signs and symptoms
Hypotension may occur
Treatment consists of gastric lavage and supportive measures
Extra pyramidal symptoms may be treated with anticholinergic, antiparkinsonism drug
Hypotension may be managed with fluid replacement